Sequence 1: | NP_572285.2 | Gene: | Grip / 50391 | FlyBaseID: | FBgn0029830 | Length: | 1058 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_008970.2 | Gene: | PTPN21 / 11099 | HGNCID: | 9651 | Length: | 1174 | Species: | Homo sapiens |
Alignment Length: | 408 | Identity: | 82/408 - (20%) |
---|---|---|---|
Similarity: | 130/408 - (31%) | Gaps: | 135/408 - (33%) |
- Green bases have known domain annotations that are detailed below.
Fly 610 SGSLRSGDILLAVDQHPVQHFNVDALLKEEGRSQNPSHSSSDFTTLTIKRIVLPDFLP------M 668
Fly 669 SSPIYSNCP---------ASGI-----------NLGMGMGVSTS-------TDHDLYSSAYVTAG 706
Fly 707 KYADC-----VSLKSRTPQP---------DYFRVPSMDDASLQSVQLRSGSGSNGGNQAANSWST 757
Fly 758 GVNSRSYVAPPNTQSLTTELPEEEDEQEQMYPGYELNRYASVDCTALPPPMENKVYGSAAS--SS 820
Fly 821 SKSSGSSLHQIIFTVRLEPKGGLLGITLAGSEDITK--SITISGLVEG--GIAHKN--------- 872
Fly 873 ---GQIHVGDQLLAIDEHSVQGMP-------------LSHATSLLQNLGDLVDLKILRSHDLANG 921
Fly 922 SHLPQTQAIYAKVQRRPR 939 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Grip | NP_572285.2 | PDZ | 82..147 | CDD:294084 | |
PDZ_signaling | 183..254 | CDD:238492 | |||
PDZ_signaling | 278..375 | CDD:238492 | |||
PDZ | 496..>521 | CDD:294084 | |||
PDZ_signaling | 571..658 | CDD:238492 | 12/47 (26%) | ||
PDZ_signaling | 832..913 | CDD:238492 | 23/109 (21%) | ||
PDZ_signaling | 973..1055 | CDD:238492 | |||
PTPN21 | NP_008970.2 | B41 | 24..222 | CDD:214604 | |
FERM_N | 27..90 | CDD:286467 | |||
FERM_M | 109..220 | CDD:278785 | |||
FERM_C_PTPN14_PTPN21 | 217..307 | CDD:270009 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 396..445 | 14/58 (24%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 673..692 | 3/18 (17%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 711..745 | 7/36 (19%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 769..806 | ||||
PTPc | 896..1166 | CDD:214550 | |||
PTPc | 923..1166 | CDD:238006 | |||
Substrate binding. /evidence=ECO:0000250 | 1108..1114 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E2759_KOG0792 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |