DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip and cytip

DIOPT Version :9

Sequence 1:NP_572285.2 Gene:Grip / 50391 FlyBaseID:FBgn0029830 Length:1058 Species:Drosophila melanogaster
Sequence 2:XP_003199223.2 Gene:cytip / 100537036 ZFINID:ZDB-GENE-140106-76 Length:343 Species:Danio rerio


Alignment Length:342 Identity:66/342 - (19%)
Similarity:109/342 - (31%) Gaps:118/342 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   238 GKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSVEFSMGP--LLIEIERPMNDKLGLVLCNYTA 300
            |:||:::|.       ...::|..::|           ..|  .::.:|:..|:..|..:..|  
Zfish    52 GRTLSQSQL-------ARTHSNSLVDY-----------TDPQRTMVVLEKQDNEVFGFEVQTY-- 96

  Fly   301 AVPASGSGSSTPSSGEKIEESAGV----FIASILPASIADRCGALSVGDQVLSIDDTMIEHTAFS 361
                          |.|::.::.|    |:..:...|.|:..| |:.||.:||::...||     
Zfish    97 --------------GLKVKNTSMVEMCTFVCRVQDGSAAETAG-LTAGDIILSVNGVSIE----- 141

  Fly   362 PDEVMTILDTSTGRGYTQMQIMPAHALARRGHTTLGSPKYSFST-----LESRKSSTAGRQRQRF 421
                          |.|...|:   .|.|....||.....|.|.     ||.:........|:::
Zfish   142 --------------GSTHQNII---ELIRESSNTLKLETVSGSVMKRIELEKKMHYLKQTLREKW 189

  Fly   422 ARKSSLPLENPACGTPG---------------STGGSMGTGGIHGSSSLGMGLGLCRAESFPVLL 471
            ....||.|:.... |.|               |....||..|...||.     ..||:    ::.
Zfish   190 VELQSLTLKEKRL-TQGNLNESAQYLSVDSVMSLSSPMGRSGQRFSSD-----SSCRS----IMT 244

  Fly   472 DCSHGAGIILSETVSGSGGSGAVAIAQIVPDSVADRSGCIQAGDRIVAINKMYSLDAAAMRQLLE 536
            |.|.. |..:|.....|.           |.|..:.||            ..:.|:..|:|.:..
Zfish   245 DDSED-GAFMSSVFDDSS-----------PLSPIESSG------------SFFQLEVGALRPITR 285

  Fly   537 GGS-SRNGASNGTPANW 552
            ..| |..|:::.....|
Zfish   286 TRSISLTGSNSSLSPGW 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GripNP_572285.2 PDZ 82..147 CDD:294084
PDZ_signaling 183..254 CDD:238492 4/15 (27%)
PDZ_signaling 278..375 CDD:238492 19/102 (19%)
PDZ 496..>521 CDD:294084 4/24 (17%)
PDZ_signaling 571..658 CDD:238492
PDZ_signaling 832..913 CDD:238492
PDZ_signaling 973..1055 CDD:238492
cytipXP_003199223.2 PDZ_signaling 78..162 CDD:238492 25/122 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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