Protein Alignment DUXA and E5

DIOPT Version :9

• Sequence 1: NP_001012747.1
• Gene: DUXA / 503835
• HGNCID: 32179
• Length: 204
• Species: Homo sapiens
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 229
• Identity: 45/229 - (19%)
• Similarity: 83/229 - (36%)
• Gaps: 79/229 - (34%)

Human    16 RRCRTKFTEEQLKILINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPEAET 80
            :|.||.|:..||..|.:.|....|...|.:::||..::..|:::::||||||.:|   ||.:.|.
  Fly   304 KRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKH---KRMQQEG 365

Human    81 LESSQSQ--------------GQDQP-----------------------------------GVEF 96
            .:.|.::              |:|..                                   |.|.
  Fly   366 GDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEM 430

Human    97 QSREARRCR----------------------TTYSASQLHTLIKAFMKNPYPGIDSREELAKEIG 139
            .:.|.:|.|                      .|.|..|.|.|::...::    :..:....::..
  Fly   431 DAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQH----LQQQHHQQQQHF 491

Human   140 VPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQ 173
            :.:.: |::.:.|......:|:||...|.|:|.|
  Fly   492 IQQQQ-QLYLREREREREREREREREKSRERENQ 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUXA	NP_001012747.1	homeodomain	16..74	CDD:238039	20/57 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..101		8/76 (11%)
		Homeobox	105..155	CDD:278475	8/71 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..204		5/11 (45%)
E5	NP_524825.1	Homeobox	307..359	CDD:278475	19/54 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910