Protein Alignment CG34401 and ZSWIM4

DIOPT Version :9

• Sequence 1: NP_001356949.1
• Gene: CG34401 / 50356
• FlyBaseID: FBgn0085430
• Length: 2371
• Species: Drosophila melanogaster
• Sequence 2: XP_016882642.1
• Gene: ZSWIM4 / 65249
• HGNCID: 25704
• Length: 1122
• Species: Homo sapiens
• Alignment Length: 2070
• Identity: 381/2070 - (18%)
• Similarity: 570/2070 - (27%)
• Gaps: 1001/2070 - (48%)

  Fly    63 PPFGGAGASGSCTPG------GNGTAMANTSTCGRHYEVSTLAELAARCVASYIPFELVEHVYPP 121
            ||  .|..|..|..|      |.|.|...    ||   ...|.:|:|:.||....||.||..:..
Human     3 PP--AAKRSRGCPAGPEERDAGAGAARGR----GR---PEALLDLSAKRVAESWAFEQVEERFSR 58

  Fly   122 VPEQLQLRIAFWSFPDNEEDIRLYSCLA-------NSSADEFNRGDSLFRLRAVKDPLQIGFHLS 179
            |||.:|.||.|||||.:|.:|.:||.|.       :.:...|.||..|.:..||...||:|||||
Human    59 VPEPVQKRIVFWSFPRSEREICMYSSLGYPPPEGEHDARVPFTRGLHLLQSGAVDRVLQVGFHLS 123

  Fly   180 ASVVNQ----TPRAYFNVAVTFDRRRISSCNCTCTS-SAYWCSHVVAVCLHRIHCPQEVCLRAPV 239
            .::...    .|...::|:::|||.:|:|.:|.|.: ..::|:||||:.|:||....:|.||.|:
Human   124 GNIREPGSPGEPERLYHVSISFDRCKITSVSCGCDNRDLFYCAHVVALSLYRIRHAHQVELRLPI 188

  Fly   240 SESLTRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSAQPTAINTVCGAPDPTAGASINDQT 304
            ||:|:::.|||||||.|||||....::|||||||.||:| ...:.||.|.|||||||||.|.|..
Human   189 SETLSQMNRDQLQKFVQYLISAHHTEVLPTAQRLADEIL-LLGSEINLVNGAPDPTAGAGIEDAN 252

  Fly   305 SWYLDEKTLHNNIKRILIKFCLPAPIVFSDVNYLTNSAPPAAAEWSSLLRPLRGREPEGMWNLLS 369
            .|:|||:.:...:|::|           |:..|...|            :.||        ::.|
Human   253 CWHLDEEQIQEQVKQLL-----------SNGGYYGAS------------QQLR--------SMFS 286

  Fly   370 IVREMYRRCDRNAVRLLEIITEECLYCDQILIWWFQTKLALMMGSHGHSGGKHSNTHSNSTALQH 434
            .||||.|..|.|..|:|.::||:.|...::.:|                       ......:..
Human   287 KVREMLRMRDSNGARMLILMTEQFLQDTRLALW-----------------------RQQGAGMTD 328

  Fly   435 ACSSLCDEIVALWRLAALNPGLAPDERDMLHAQFTAWHLKILDRVVKSRMMPSYTNKHQQNSRSE 499
            .|..|.||:.|||....|:|...|:||       ..| |::|.|..|..:.|.....:..:..|
Human   329 KCRQLWDELGALWVCVVLSPHCKPEER-------AGW-LQLLSRWDKLDVCPLEEGNYSFDGPS- 384

  Fly   500 TELFIGFKPAIEACYLDWEGYPIPGVTHTHD---TNPIYYSPFTCFKHTDLKGESNNPGQLNATQ 561
                  .:|.:.         |.||.....:   |:|         :||..            .:
Human   385 ------LQPTMA---------PAPGSEEEEEVAATSP---------RHTVF------------GR 413

  Fly   562 ALMSNNKHYNYFSSSSDHGMHAGAFKQRLDRPFRESRFYTNPADLDGGAALAGGGSGRFSTGLGS 626
            ||::...|:|            .|:.||:                     ||....|...||
Human   414 ALLAGELHWN------------DAYLQRI---------------------LASDSYGPSLTG--- 442

  Fly   627 VAVGGAGAGGLGQMSGGVNNSVGGSAAA---EVNP--VQQQLPSGSAGVGASVTNAKVVVATDGN 686
                                ||||....   :..|  :.:..|:..|.|
Human   443 --------------------SVGGDKPTFDPQGRPLWLGEPFPTACARV---------------- 471

  Fly   687 RSSASSEGFCENDDFGGDTSSSHNYCPPGQAVVPGQKSALTESDSQSSFDAVSHQSKDEPPVGGV 751
                             ||..:|.|  |.||:
Human   472 -----------------DTLRAHGY--PRQAL--------------------------------- 484

  Fly   752 GVAVGVEQALSTSDTSSASSSSSSASTASGSSNSSTSSMLMAGQEATVGVGGAVQQTTRRLSKDE 816
                                     ..||...|                        |.||.:..
Human   485 -------------------------RLASAIIN------------------------TLRLQQRH 500

  Fly   817 SFSSSSDEFNQGGVGGSAGRVAMASSGSGSGAGDTVAVGSGSTAGGDLTPV-PSTSAAARAALAA 880
            ...|...:..:...|..|                             |:|: |......:.:...
Human   501 QLESYKQQKKETWAGVWA-----------------------------LSPLFPPAELLQKGSTCI 536

  Fly   881 SSTGPVISASPHLAASAAGGLGVLGVGADQPCTSSAHAARALAAAVAASSDKPHVFSNVRPTEDA 945
            ::|              .|.:|       .|........|||
Human   537 TNT--------------EGWVG-------HPLDPIGCLCRAL----------------------- 557

  Fly   946 WDILLARAEGLHAHGHGAEACILAVRLAEQMLANPPNLLLELPPAPKRKGKKQNVNPISHQLTVV 1010
                             .|||    ||.|:.|...|:...|     |||...|:| |:..
Human   558 -----------------LEAC----RLEEETLTLYPDSGPE-----KRKVAYQHV-PVPG----- 590

  Fly  1011 ASATLSKCAFLCTVLSENSEHYHIGFRICLFALEMPRPPASTKPLEVKLANQEADILALLKRLPL 1075
                           |....:..:...:.|..|...|........:.|:...|..:||||:.:.|
Human   591 ---------------SPGESYLVLALEVALLGLGQQRALPEGLYAQDKVVRNEEQLLALLEEVEL 640

  Fly  1076 GSAELQVIRERAE-QLRSGTFKTRGEAL----LPIN-LATFIFDALVTLSPLGGSTIVPGVASTS 1134
            ....:||:|::|. .|..|.|...||.|    :|:: .|.::|.||:
Human   641 DERLVQVLRKQAGLLLEGGPFSGFGEVLFRESVPMHTCARYLFTALL------------------ 687

  Fly  1135 GVSSAAGKSMVNTGTRLLLYKHNSDESLGFDAAVAALGLKANVSEAEHPLLCEGTRRQRGDLALT 1199
                                .|:.|  |.:..|:.|:.|
Human   688 --------------------PHDPD--LAYRLALRAMRL-------------------------- 704

  Fly  1200 LLSHYKDEPRKIAKIMEKLLDRDIHTLLNAPLLPAYYSSNPPVRTRSNQPTRREDHDYGGGSGCA 1264
                                          |:|...:.:..|             |
Human   705 ------------------------------PILETAFPAGEP-------------H--------- 717

  Fly  1265 SSNCNPVANLCELLPADYGSVGGNSRPHSSTSAELELSMCALSMASSGSQSGGVQGMVPTTNAAG 1329
                          |:...|:..|..|.......||...|.|:                :|....
Human   718 --------------PSPLDSIMSNRFPRWFILGHLETRQCELA----------------STMLTA 752

  Fly  1330 TTGTPSSSSTTVSGSQNPNGNPSGSGGGGNGGGGNGGGGGGGGGGGGSTSSRSKESRYKGKRAYP 1394
            ..|.|....|.:...|....:|:
Human   753 AKGDPKWLHTVLGSIQQNIHSPA------------------------------------------ 775

  Fly  1395 SIPNQPSEASAHFMFELAKNVLTKAGGNSSTSLFTQASTSQNHHGPHRALHMCAFQLGLYALGLH 1459
                        .:|:||::....|         |..|..     |...|...|.:|||..:.:.
Human   776 ------------LLFKLAQDACKTA---------TPVSAP-----PDTTLLGIALELGLQVMRMT 814

  Fly  1460 NCVSPNWLSRTYSSHVSWILGQAMEIGAPAISFLIDTWEAHLTPPEAAGMADRASRGWDSNMVYP 1524
            ..|. .|..|   ..|.|::..|.|||..|:..::..|.:..||.|||.:
Human   815 LNVM-TWRRR---EMVRWLVSCATEIGPQALMNIMQNWYSLFTPVEAATI--------------- 860

  Fly  1525 AAELALSVLPHAAALNPNEIQRAILQCKEQSDLMLERACLTVETAAKGGGVYPEVLFQVARYWYE 1589
               :|::...||..|.                       |.::|:.:      |.|:..||
Human   861 ---VAVTGTTHATLLR-----------------------LQLDTSRR------EELWACAR---- 889

  Fly  1590 LYMRNTPNNSEFEPHDDTMDHSAVSLSALIESQQQHELQQQQQAVQQQQAVQQQQQVVQQQQQVV 1654
                             |:
Human   890 -----------------TL---------------------------------------------- 891

  Fly  1655 QQQQQLGMPNSVVPGGVGPGPGLPVAVQPPVVGSVQNPQAQFQPVGVASLAPLGLAQYPPYSFCQ 1719
                                 .|..|::.|     ||                  ...|..:.|
Human   892 ---------------------ALQCAMKDP-----QN------------------CALPALTLC- 911

  Fly  1720 GLYAHHHNMSYPPGQMQMFISAGPPPPPQAYGGYQQPPPQQPPNPQQQQQVVQQQVQQQQVVQQQ 1784
                                                                             
Human   912 ----------------------------------------------------------------- 911

  Fly  1785 QQQVQMAGQAPPGHPGQQGHPGQPPSGFQPQPPPGAFQALPPQAYQAMQAGPPGPPMGPPQGYYG 1849
                            ::.|              .||:|    |||.:.....|
Human   912 ----------------EKNH--------------SAFEA----AYQIVLDAAAG----------- 931

  Fly  1850 PPPPPPPNGPPGVGVGVGVGVGVGVMPMRQHQHQHPVYPFMQQAPPQPPQQQQPPPSQPPVRQRQ 1914
                                 |:|      |.|...|..:|:
Human   932 ---------------------GLG------HAHLFTVARYME----------------------- 946

  Fly  1915 PHQFTPTQLRYLLAAYNVGMLAMETLARRVHDDRPQAKYARNPPYGEDVKWLLRISKKLGTQYLH 1979
             |:..|      |.||.:..||:..|:...:.|        :.|...||.|...:|..||...|.
Human   947 -HRGLP------LRAYKLATLALAQLSIAFNQD--------SHPAVNDVLWACSLSHSLGRHELS 996

  Fly  1980 QFCICAVNSIVSPFVLHDVAIE---SAHYLGRNNHQMVMQHLRSALTPLVQKCQQM------YIQ 2035
            ......:.||....:|.|:...   ||..||....:...:.|.:...||   ||.:      ||.
Human   997 AIVPLIIRSIHCAPMLSDILRRWTLSAPGLGPLGARRAAKPLGADRAPL---CQLLDAAVTAYIT 1058

  Fly  2036 CIHQKLYHLTQGDYEEFASIVVAARAAFQITPEGNAQFKDWLQSIKRSKSCKKEL 2090
            ..|.:|.|::...|.:|...:..||..|.:.|:|:.||..:|:::|::...||:|
Human  1059 TSHSRLTHISPRHYGDFIEFLGKARETFLLAPDGHLQFSQFLENLKQTYKGKKKL 1113

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3615
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900