|
Fly 2 DRFSFDDSIRFEEDSLCSWSSEPESLCNNWRGWKKPAAGSGAGNGGLSGMGGMAVAGGSGAPPFG 66
:||||:||.|||||||||:.||.||||.|||||:|.:||..:..|| |
Rat 12 ERFSFEDSDRFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTGG------------------G 58
Fly 67 GAGASGSCTPGGNGTAMANTSTCGRHYEVSTLAELAARCVASYIPFELVEHVYPPVPEQLQLRIA 131
|.|.|| ||.| |...|..|.||:|:.||.:||||:||.||||||||||||||
Rat 59 GGGGSG-------GTRM-------RDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIA 109
Fly 132 FWSFPDNEEDIRLYSCLANSSADEFNRGDSLFRLRAVKDPLQIGFHLSASVVNQ---TPRAYFNV 193
|||||:|||||||||||||.|||||.|||.|||:|||||||||||||||:||.. .|:..:||
Rat 110 FWSFPENEEDIRLYSCLANGSADEFQRGDQLFRMRAVKDPLQIGFHLSATVVPPQMVPPKGAYNV 174
Fly 194 AVTFDRRRISSCNCTCTSSAYWCSHVVAVCLHRIHCPQEVCLRAPVSESLTRLQRDQLQKFAQYL 258
||.|||.|::||:|||.:.|.||:||||:||.|||....|||||||||||:||||||||||||||
Rat 175 AVMFDRCRVTSCSCTCGAGAKWCTHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYL 239
Fly 259 ISELPQQILPTAQRLLDELLSAQPTAINTVCGAPDPTAGASINDQTSWYLDEKTLHNNIKRILIK 323
|||||||||||||||||||||:|.|||||||||||||||.|.:||::|||||.||.:|||:.|.|
Rat 240 ISELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLTDNIKKTLHK 304
Fly 324 FCLPAPIVFSDVN--YLTNSAPPAAAEWSSLLRPLRGREPEGMWNLLSIVREMYRRCDRNAVRLL 386
||.|:|:|||||| ||:::.|||||||:.||||||||||||:||||||||||::|.|.||..||
Rat 305 FCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGVWNLLSIVREMFKRRDSNAAPLL 369
Fly 387 EIITEECLYCDQILIWWFQTKLALMMGSHGHSGGKHSNTHSNSTALQHACSSLCDEIVALWRLAA 451
||:|::||..:||..||:..:.: .||..:.|....::..|....|||:|:|||:|.|||||.
Rat 370 EILTDQCLTYEQITGWWYSVRTS---ASHSSASGHTGRSNGQSEVAAHACASMCDEMVTLWRLAV 431
Fly 452 LNPGLAPDERDMLHAQFTAWHLKILDRVVKSRMMPSYTNKHQQNSRSETELFIGFKPAIEACYLD 516
|:|.|:|..|..|.||...|.||:::.| |..|:.::...||.||:||:||||.:
Rat 432 LDPALSPQRRRELCAQLRQWQLKVIENV-----------KRGQHKKTLERLFPGFRPAVEACYFN 485
Fly 517 W-EGYPIPGVTHTHDTNPIYYSPFTCFKHTDLKGESNNPGQLNATQALMSNNKHYNYFSSSSDHG 580
| |.||:||||::.....: ..|: .:.....|| .
Rat 486 WEEAYPLPGVTYSGTDRKL----ALCW----ARALPTRPG------------------------A 518
Fly 581 MHAGAFKQRLDRPFRESRFYTNPA--DLDGGAALAGGGSG--------RFS------------TG 623
..:||.::...||.. |.|| ..:.||...|.|.| |.| :|
Rat 519 SRSGALEESRPRPLP-----TEPAVRPKEPGAKRKGLGEGVSSQRGPRRLSAEGDKALHKMCPSG 578
Fly 624 LGSVAVGGAGAGGLGQMSGGVNNSVGG-SAAAEVNPVQQQLPSGSAGVGASVTNAKVVVATDGNR 687
..:..:||.|:||......|....:.. .::.|.:..:..|...|..:||
Rat 579 AKAKVLGGPGSGGKSSAGSGSKRRLSSEDSSLEPDLAEMSLDDSSLALGA--------------- 628
Fly 688 SSASSEGFCENDDFGGDTSSSHNYCPPGQAVVPGQKSALTESDSQSSFDA-VSHQSKDEPP---V 748
|...|||...|... ||| .|...|..:.|.|.......|| |......||| .
Rat 629 ---------EASTFGGFPESPPP-CPP-SAGSRGPSTFLPEPPDTYEEDAGVYFSEGPEPPTASA 682
Fly 749 GGVGVAVGV----EQALSTSDTSSASSSSSSASTASGSSNSSTSSMLMAGQEATVGVGGAVQQTT 809
|..|:..|. :...||.|:.|....:..|:.|.|..:....:..::.|: |.||
Rat 683 GRPGLLPGEVCTRDDLPSTDDSGSGLHKTKEAAPAVGEEDDDYQAYYLSAQD---GAGG------ 738
Fly 810 RRLSKDESFSSSSDEFNQGGVGGSAGRVAMASSGSGSGAGDTVAVGSGSTAGGDLTPVPSTSAAA 874
.:|..:||.|
Rat 739 ------------EEEKAEGGTG------------------------------------------- 748
Fly 875 RAALAASSTGPVISASPHLAASAAGGLGVLGVGADQPCTSSAHAARALAAAVAASSDKPHVFSNV 939
::..:|:.:
Rat 749 --------------------------------------------------------EEHDLFAGL 757
Fly 940 RP--TEDAWDILLARAEGLHAHGHGAEACILAVRLAEQMLANPPNLLLELPPAPKRKGKKQNVNP 1002
:| .|...::|.|.||.|||||:..||..|.|.||:.:|||||:|.:|.||| ||||..|:
Rat 758 KPLEQESRMEVLFACAEALHAHGYSNEASRLTVELAQDLLANPPDLKVEPPPA---KGKKNKVS- 818
Fly 1003 ISHQLTVVASATLSKCAFLCTVLSENSEHYHIGFRICLFALEMPRPPASTKPLEVKLANQEADIL 1067
:.:.|.||:.||:|.|||.|||||..||:::.||:.:||||:.|||||||.||||||.||:::.
Rat 819 -TSRQTWVATNTLTKAAFLLTVLSERPEHHNLAFRVGMFALELQRPPASTKALEVKLAYQESEVA 882
Fly 1068 ALLKRLPLGSAELQVIRERAEQLRSGTFKTRGEALLPINLATFIFDALVTLSPLGGSTIVPGVAS 1132
||||::|.|.:|:..||.|||:||.||. .....:||:.||:||||.| .:| |.|
Rat 883 ALLKKIPRGPSEMSTIRCRAEELREGTL-CDYRPVLPLMLASFIFDVL--CAP---------VVS 935
Fly 1133 TSGVSSAAGKSMVNTGTRLLLYKHNSDESLGFDAAVAALGLKANVSEAEHPLLCEGTRRQRGDLA 1197
.:| |....::..| :...||.|||:|||||||:|..|||||||||||||||::||||
Rat 936 LTG-SRPPSRNWSN--------EMPGDEELGFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLA 991
Fly 1198 LTLLSHYKDEPRKIAKIMEKLLDRDIHTLLNAP-LLPAYYSSNPPVRTRSNQPTRREDHDYGGGS 1261
|.|:..|||:..|:.||::|||||:..| :.| .|.::|||:.|.......|::. |:
Rat 992 LALMITYKDDQAKLKKILDKLLDRESQT--HKPQTLSSFYSSSRPATANQRSPSKH-------GA 1047
Fly 1262 GCASSNCNPVANLCELLPADYGSVGG---------------NSRPHSSTSAELELSMCALSMASS 1311
..|.....|:.: ....||..|:|.| .|.|||... .:...
Rat 1048 PSAPGALQPLTS-SSAGPAQPGNVAGAGPAPTEGFTEKNVPESSPHSPCE----------GLPPE 1101
Fly 1312 GSQSGGVQGMVPTTNAAGTTG-----------------------------TPSSSSTTVSGSQNP 1347
.:.:...:|.||:..|.|:.| |.|.||.|:|.....
Rat 1102 AALTPRPEGKVPSRLALGSRGGYNGRGWGSPGRPKKKHTGMASIDSSAPETTSDSSPTLSRRPLR 1166
Fly 1348 NGNPSGSGGGGNG------------GGGNGGGGGGGGGGGGSTSSRSKESR-YKGKRA---YPSI 1396
.|....|.|.|.. |..:..|.......||:.:...:..| |||:|. .|.:
Rat 1167 GGWAPASWGRGQDSDSISSSSSDSLGSSSSSGSRRASASGGARAKTVEVGRCYKGRRPESHAPHV 1231
Fly 1397 PNQPSEASAHFMFELAKNVLTKAGGNSSTSLFTQASTSQNHHGPHRALHMCAFQLGLYALGLHNC 1461
|||||||:|||.|||||.||.|||||||||:||..|:|..|.||||.||:|||::|||||||||.
Rat 1232 PNQPSEAAAHFYFELAKTVLIKAGGNSSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNF 1296
Fly 1462 VSPNWLSRTYSSHVSWILGQAMEIGAPAISFLIDTWEAHLTPPEAAGMADRASRGWDSNMVYPAA 1526
|||||||||||||||||.|||||||:.|::.|::.|:.||||||.|.:||||||..|||||..||
Rat 1297 VSPNWLSRTYSSHVSWITGQAMEIGSAALTILVECWDGHLTPPEVASLADRASRARDSNMVRAAA 1361
Fly 1527 ELALSVLPHAAALNPNEIQRAILQCKEQSDLMLERACLTVETAAKGGGVYPEVLFQVARYWYELY 1591
|||||.||||.||||||||||::|||||.:||||:||:.||.|||||||||||||:||..|:.||
Rat 1362 ELALSCLPHAHALNPNEIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWFWLY 1426
Fly 1592 MRNTPNNSEFEPHDDTMDHSAVSLSALIESQQQHELQQQQQAVQQQQAVQQQQQVVQQQQQVVQQ 1656
......:| |....|.|.|.
Rat 1427 EETAGGSS-------TAREGAASCSG--------------------------------------- 1445
Fly 1657 QQQLGMPNSVVPGGVGPGPGLPVAVQPPVVGSVQNPQAQFQPVGVASLAPLGLAQ-YPPYSFCQG 1720
:.:...|.| |.|||.....| |: :||.||:.|....|. .|..|....
Rat 1446 -------SGMRAAGEG-GRGLPEGRGAP--GT--------EPVTVAAAAVTAAATVVPVISVGSS 1492
Fly 1721 LYAHHHNMSYPPGQMQMFISAGPPPPPQAYGGYQQPPPQQPPNPQQQQQVVQQQVQQQQVVQQQQ 1785
||. .|| :..|..|....|...| |..|.:||
Rat 1493 LYP-------GPG-----LGHGHSPGLHPYTALQ---PHLPCSPQ-------------------- 1522
Fly 1786 QQVQMAGQAPPGHPGQQGHPGQP-----PSGFQPQPPPGAF------QALPPQAYQAMQAGPPGP 1839
.:...|.|.|| ..|..:| ||...||....|| .::.|.:..|.....|.|
Rat 1523 ---YLTHPAHPAHP--MPHMPRPAVFPVPSSAYPQGVHPAFLGAQYPYSVTPPSLAATAVSFPVP 1582
Fly 1840 PMGPPQGYYGPPPPPPPNGPPGVGVGVGVGVGVGVMPMRQHQHQHPVYPFMQQAPPQPPQQQQPP 1904
.|.|...: |.:..||:.:...|.: ...|....:|.:|.| ..|....||.
Rat 1583 SMAPITVH-------PYHTEPGLPLPTSVAL--------SSVHPASTFPAIQGA-SLPALSTQPS 1631
Fly 1905 P-----SQPPVRQRQPHQFTPTQLRYLLAAYNVGMLAMETLARRVHDDRPQAKYARNPPYGEDVK 1964
| ..||..:......:|..|.:|.|||.|||||:|.|.||.|:|.|. .::|:|||.:|||
Rat 1632 PLVSGGFPPPEEETHSQPVSPHSLHHLHAAYRVGMLALEMLGRRAHNDHPN-NFSRSPPYTDDVK 1695
Fly 1965 WLLRISKKLGTQY 1977
|||.::.|||.::
Rat 1696 WLLGLAAKLGDRH 1708
| 
