Protein Alignment Dora and zswim6

DIOPT Version :10

• Sequence 1: NP_001356949.1
• Gene: Dora / 50356
• FlyBaseID: FBgn0085430
• Length: 2371
• Species: Drosophila melanogaster
• Sequence 2: XP_031749918.1
• Gene: zswim6 / 100490710
• XenbaseID: XB-GENE-984745
• Length: 1168
• Species: Xenopus tropicalis
• Alignment Length: 738
• Identity: 196/738 - (26%)
• Similarity: 290/738 - (39%)
• Gaps: 188/738 - (25%)

  Fly    69 GASGSCTPG---GNGTAMANTST---CGRHYEVSTLAELAARCVASYIPFELVEHVYPPVPEQLQ 127
            |.|.||.||   |..:..|..|.   .||..:..:|.::|||.||...||:.||..:..:||.:|
 Frog    18 GFSSSCRPGQRTGGASCGAGGSAHGLSGRTQDPESLLDIAARKVAEKWPFQRVEERFERIPEPVQ 82

  Fly   128 LRIAFWSFPDNEEDIRLYSCLANSSAD-------------------------------------- 154
            .||.:||||.:|.:|.:||.......|
 Frog    83 RRIVYWSFPRSEREICMYSSFNTGGEDGAGAASGGVSAAGASGTAVGAGAAAVGAASVASTAGVS 147

  Fly   155 -----------EFNRGDSLFRLRAVKDPLQIGFHLSASV----VNQTPRAYFNVAVTFDRRRISS 204
                       .|.||.:|.....|.:.||:|||||.:|    |...|....|||::|||.:|:|
 Frog   148 ASGETNDENRLPFRRGIALLEGGCVDNVLQVGFHLSGTVTEPAVQSEPGTVCNVAISFDRCKITS 212

  Fly   205 CNCTC-TSSAYWCSHVVAVCLHRIHCPQEVCLRAPVSESLTRLQRDQLQKFAQYLISELPQQILP 268
            ..|:| ....::|:||||:.|:||..|.:|.|..|:||:|.::.|||||||.||||:....::||
 Frog   213 VTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLP 277

  Fly   269 TAQRLLDELLSAQPTAINTVCGAPDPTAGASINDQTSWYLDEKTLHNNIKRILIKFCLPAPIVFS 333
            |||:|.||:|| |.:.||.|.|||||||||||:|:..|:|||:.:...:|.
 Frog   278 TAQKLADEILS-QNSEINQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKL-------------- 327

  Fly   334 DVNYLTNSAPPAAAEWSSLLRPLRGREPEGMWNLLSIVREMYRRCDRNAVRLLEIITEECLYCDQ 398
               :|:......:.:..:|              |.:.||||.:..|.|..|:|.:|||:.:...:
 Frog   328 ---FLSQGGYHGSGKQLNL--------------LFAKVREMLKMRDSNGARMLTLITEQFMADPR 375

  Fly   399 ILIWWFQTKLALMMGSHGHSGGKHSNTHSNSTALQHACSSLCDEIVALWRLAALNPGLAPDERDM 463
            :.:|                       ....||:......|.||:.|||....|||....:::.:
 Frog   376 LSLW-----------------------RQQGTAMTDKYRQLWDELGALWMCIVLNPHCKAEQKAI 417

  Fly   464 LHAQFTAW------------HLKILDRVVKSRMMPSYTNKHQQNSRSETELFIGFKPAIEACYLD 516
            ...|...|            |...|..:..:  :|...|.:|.:|.......  |..|||||.|.
 Frog   418 WLKQLKKWNSVDVCPWEDGNHGNELPNLTNA--LPQGGNANQDSSHRPHRTV--FTRAIEACDLH 478

  Fly   517 WEGYPIPGVTHT--------HDTN----------PIYYS--PFTCFKHTDLKGESNNPGQLNATQ 561
            |:...:..:..:        ||..          |:::.  |..|.:...|:........|....
 Frog   479 WQDSHLQHIISSDLYTNYCYHDDTENSLFDSRGWPLWHEHVPTACARVDALRSHGYPREALRLAI 543

  Fly   562 ALMS-----NNKHYNYFSSSSDHGMHAGAFKQRLDRPFRESRFYTNPADLDG--GAALAGGGSGR 619
            |:::     ..|....|.......:|.|               .|:..:|:|  |..|...|: .
 Frog   544 AIVNTLRRQQQKRMEIFRLQKKELVHKG---------------ITSITNLEGWVGHPLDPIGT-L 592

  Fly   620 FSTGLGSVAVGGAGAGGLGQMSGGVNNSVGGSAAAEVNPVQQQLPSGSAGVGASVTNAKVVVATD 684
            ||:.:.:..|...|..|....:.|    .|...:.|   .|...|......|.|.....|.||..
 Frog   593 FSSLMEACRVDDEGFHGFSDFADG----FGHCKSLE---YQHLSPHKFLEEGESYLTLAVEVALI 650

  Fly   685 GNRSSA-------SSEGFCENDD 700
            |.....       :.|..|.|::
 Frog   651 GLGQQRIMPDGLYAQEKVCRNEE 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dora	NP_001356949.1	SWIM	138..>276	CDD:443750	62/191 (32%)
zswim6	XP_031749918.1	SWIM	160..>286	CDD:443750	58/125 (46%)