DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and Igsf9

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	314	Identity:	71/314 - (22%)
Similarity:	111/314 - (35%)	Gaps:	92/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PLHLME-LRILLLCLPTL----LLATTLEPD---------------QKSILTDNDWKKL------ 53
            |||::| ||...| ||..    |.:..::||               :...:.|..|.:.
Mouse    51 PLHVIEWLRFGFL-LPIFIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLD 114

  Fly    54 ------------WMRGGINGDSKLDNNLDSSDSP--MFEDSELMAHNTTVQLGGTAFLVCKVSGV 104
                        |:...:|...:.      .::|  :.|..||.|          ..|.|...|.
Mouse   115 QHSPEQDFANGSWVHLTVNSPPQF------QETPPLVLEVKELEA----------VTLRCVARGS 163

  Fly   105 DRVGVNWNQISWIRRRDWHILSSG-AQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQV 168
            .:..|.|.    .|.:|   |..| .|:...:             .||.|:.|:|...|.|.||.
Mouse   164 PQPYVTWK----FRGQD---LGKGQGQVQVQN-------------GTLWIRRVERGSAGDYTCQA 208

  Fly   169 STPTGIISHFVNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRL--INY 231
            |:..|.|:|...|.|:.|...::......|:....::|.|..|..|....|.::|....:  |:.
Mouse   209 SSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISR 273

  Fly   232 VDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSASN----TEPASIYVFV 281
            :.||..|.::        ..|.::..|..|:|:|||..||    ...||.|:.|
Mouse   274 LQSRVRILVD--------GSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTV 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	24/97 (25%)
		Ig_3	193..271	CDD:404760	18/79 (23%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	3/4 (75%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	14/59 (24%)
		Ig	136..223	CDD:386229	29/122 (24%)
		Ig_3	227..305	CDD:372822	18/85 (21%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900