DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and dscama

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	198	Identity:	52/198 - (26%)
Similarity:	80/198 - (40%)	Gaps:	51/198 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKF 155
            :|....|.|.|:|.|..     ::||.|..|  .:::||.:..|          |.|...|.:..
Zfish   328 VGSQVSLSCSVTGSDEF-----ELSWYRNGD--KINTGANIRMN----------GINKENLVMDG 375

  Fly   156 VQRRDHGMYEC-------------QVSTPTG---IISHFVNLQVVVPEAFILGSGELHVDMGSTI 204
            :.:.|.|:|:|             ||....|   |:|.| :.:||.|..|              :
Zfish   376 MAKSDGGVYQCFSRKAKMSAQDFVQVILEDGTPKILSAF-SEKVVGPNDF--------------V 425

  Fly   205 NLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSA 269
            :|.|.::.:|.|.  :.|..:|.:: ..|||..|....|......|.|.|...||.|||.|.|:.
Zfish   426 SLTCHVKGTPQPA--ITWTLDDEVV-AKDSRHRIVHSITAEGNVVSYLNISHIQVRDSGVYRCTC 487

  Fly   270 SNT 272
            :|:
Zfish   488 NNS 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	26/107 (24%)
		Ig_3	193..271	CDD:404760	21/77 (27%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653	21/90 (23%)
		I-set	408..502	CDD:333254	29/101 (29%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810