DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and aebp1b

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	288	Identity:	47/288 - (16%)
Similarity:	89/288 - (30%)	Gaps:	109/288 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ILLLCLPTLLLATTLEPDQKSILTDNDWKKLWMRGGINGDSKL------------DNNLDSSDSP 75
            :::|||..|:.:                   |...|:...||.            |.|:.|.:..
Zfish    10 LVVLCLSLLVPS-------------------WEVNGLTEHSKSEISHTDREQHVEDRNVTSVEDL 55

  Fly    76 MFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAI 140
            :  ..:::....|:::|....|:||||. |...:||            :..:|.::.|......:
Zfish    56 L--QVKIIPPYATIEVGQHKQLLCKVSS-DAKNINW------------VSPNGEKVLTKHGNLKV 105

  Fly   141 LHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVV-------------------- 185
             |..||.:.:|.:......:.|:|:|..:.........|.|.:::
Zfish   106 -HNHGSVLSSLTVLNANLNNAGIYKCVATNGDTESQATVKLDIILKRMRRDTDRKGREKRLKEPK 169

  Fly   186 -------------PEAFILGSGE--------LHVDMGSTINLVCIIEKSPTPPQY---------V 220
                         |::...|.||        .:.:..:|:....:...:..|.:|         .
Zfish   170 PSKKPKASKPTKKPKSEKKGKGEKGGKKKGKKNREESTTVATTTVAPTTTVPMEYEEFYDPEPDQ 234

  Fly   221 YWQKNDRLINYVDSRRDITIETTPGPRT 248
            ||.:            |...|||...||
Zfish   235 YWDE------------DFPAETTTVART 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	21/96 (22%)
		Ig_3	193..271	CDD:404760	13/73 (18%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	2/12 (17%)
		Ig strand E	250..254	CDD:409353
		Ig strand F	264..269	CDD:409353
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	21/106 (20%)
		IG_like	62..145	CDD:214653	20/96 (21%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900