DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and paplna

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	297	Identity:	69/297 - (23%)
Similarity:	108/297 - (36%)	Gaps:	88/297 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPMVPPRLLLRLRRPLHLMELRILLLCLPTLL------LATTLEPDQKSILTDNDWKKLWMRGGI 59
            :|:.|.|         |..:|...||..|..|      |......|::      |.:.:::  .:
Zfish   873 VPVDPTR---------HEQQLDGSLLVGPITLQDSGWFLCVATRDDKR------DHRYIYL--SV 920

  Fly    60 NGDSKLDNN-----LDSSD--------------SPMFEDSELMAHNTTVQLGGTAFLVCK---VS 102
            :|.|:  ||     :|||.              ||:.|          .:.|.||.|.|.   ||
Zfish   921 SGSSQ--NNAGISEVDSSQSYTSQSSSRFNIDYSPLVE----------ARAGQTAKLQCSVLPVS 973

  Fly   103 GVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQ 167
            .:..|.::|::             :|..|  |..|.: .|:.|    ||.||.:...|.|:|.|.
Zfish   974 AIHAVTIHWSR-------------AGQPL--NSLRHS-QHSDG----TLVIKQLTADDSGLYTCT 1018

  Fly   168 VSTPTGIISHFVNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYV 232
            |:.........|.|:|:..........::.|..|||..|.|::.....   .|.|.:|...:...
Zfish  1019 VTDAQKFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGENV---NVGWSRNGVPVRPD 1080

  Fly   233 DSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSA 269
            ..|..::.:.|        ||:...|..|.|.|||:|
Zfish  1081 GHRVHVSADGT--------LILNNVQSVDEGTYTCNA 1109

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	26/99 (26%)
		Ig_3	193..271	CDD:404760	20/77 (26%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	3/4 (75%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449	10/41 (24%)
		IGc2	960..1022	CDD:197706	24/81 (30%)
		I-set	1039..1121	CDD:333254	20/82 (24%)
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900