DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr12 and NCAM2

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_011527877.1 Gene:NCAM2 / 4685 HGNCID:7657 Length:874 Species:Homo sapiens


Alignment Length:250 Identity:63/250 - (25%)
Similarity:106/250 - (42%) Gaps:36/250 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 LEPDQKSILTDNDWKKLWMRGGINGDS-----KLDNNLDSSDSPMFEDSELMAH-----NTTVQL 91
            :|.::|.||..:: .:|.:|..||.|.     :..|.....:...|....:..|     |.|...
Human   276 IEENEKYILKGSN-TELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYE 339

  Fly    92 GGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFV 156
            .|...|||     |..|....:|:|.|..|....:.|.:  :.|.|..:....||:  :|.||.|
Human   340 NGQVTLVC-----DAEGEPIPEITWKRAVDGFTFTEGDK--SLDGRIEVKGQHGSS--SLHIKDV 395

  Fly   157 QRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVY 221
            :..|.|.|:|:.::..|.....:.|.:.....||......:...|:.||:.|.::.:  ||..::
Human   396 KLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSN--PPASIH 458

  Fly   222 WQKNDRLINYVDSRRDITIETTPGPRTQS--RLIIREPQVT---DSGNYTCSASN 271
            |:: |:|:        :..:.|...:|.|  |.:|.|...|   |.|.|.|:|:|
Human   459 WRR-DKLV--------LPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 27/96 (28%)
Ig_3 193..271 CDD:404760 21/82 (26%)
Ig strand B 204..208 CDD:409353 2/3 (67%)
Ig strand C 219..223 CDD:409353 0/3 (0%)
Ig strand E 250..254 CDD:409353 2/5 (40%)
Ig strand F 264..269 CDD:409353 2/4 (50%)
NCAM2XP_011527877.1 Ig1_NCAM-2 46..137 CDD:143274
I-set 47..136 CDD:254352
I-set 142..218 CDD:254352
IGc2 153..214 CDD:197706
Ig 233..326 CDD:299845 11/50 (22%)
I-set 240..323 CDD:254352 11/47 (23%)
Ig5_NCAM-2 325..422 CDD:143278 28/105 (27%)
IG_like 333..420 CDD:214653 26/95 (27%)
IG_like 438..515 CDD:214653 21/77 (27%)
IGc2 439..507 CDD:197706 21/76 (28%)
FN3 521..613 CDD:238020
fn3 619..703 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.