DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and klg

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	74/327 - (22%)
Similarity:	116/327 - (35%)	Gaps:	101/327 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GGINGDSKLDNNLDSSDS-PMFEDSELMAHNTTVQL--------------GGTAFLVCKVSGVDR 106
            ||...::.:.|...:|.| ...:.|.:.|...|..|              |.|..|.|:|..:..
  Fly    65 GGFAVEAAISNRGSNSRSMSNVQQSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVENLGN 129

  Fly   107 VGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTP 171
            ..:.|       ||..::|::...:.|.|||..::     :.:.|:|..::.:|.|.|.||:|..
  Fly   130 FVLLW-------RRGTNVLTASNIMVTRDERVRLI-----DGYNLEISDLEPQDAGDYVCQISDK 182

  Fly   172 TGIISHFVN------LQVVVPEAF--ILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRL 228
                   :|      ::::||.:.  |..||:|....|..|.|.|....:|.|.  :||.|.
  Fly   183 -------INRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPS--IYWTKK--- 235

  Fly   229 INYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSASN--------------TEPASIYV 279
                ......|.....||    .|.:.:.:...:|.|.|:|.|              ..|..|.|
  Fly   236 ----SGANKSTARIGDGP----ILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQV 292

  Fly   280 ----------FVSK------GDNMAAISRRKTS----SADR---LTHIFRSMLAPCLLLNTVVVR 321
                      |.:|      .|.:|.:|..:.|    |.||   .|...|.||         .:|
  Fly   293 EKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATRANRHML---------TIR 348

  Fly   322 HI 323
            ||
  Fly   349 HI 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	24/116 (21%)
		Ig_3	193..271	CDD:404760	20/77 (26%)
		Ig strand B	204..208	CDD:409353	2/3 (67%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	13/58 (22%)
		IG_like	109..195	CDD:214653	22/104 (21%)
		Ig	118..191	CDD:143165	20/91 (22%)
		IG_like	205..274	CDD:214653	21/81 (26%)
		IGc2	213..273	CDD:197706	18/72 (25%)
		IGc2	301..367	CDD:197706	16/59 (27%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810