DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and Ama

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	51/222 - (22%)
Similarity:	88/222 - (39%)	Gaps:	40/222 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 NLDS-SDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNW---------NQISWIRRRDW 122
            :||| ..:|:...   ::.:....:|.:....|.|..|.::.|:|         |.:
  Fly    25 SLDSVLSAPVISQ---ISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSV-------- 78

  Fly   123 HILSSGAQLYTNDERFAILHT----PGSNMWTLQIKFVQRRDHGMYECQV-STPTGIISHFVNLQ 182
             :||....|...|:|:.:..|    .||.::|.:|:.::..|.|.||||| .:.|..::..::||
  Fly    79 -VLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQ 142

  Fly   183 VVVPEAFILGSGE-LHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGP 246
            :..|......:.: ..|..|..:.|.|.....|.|.  :.|.:....:  :.:...:..|.|
  Fly   143 IKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPT--ISWAREHNAV--MPAGGHLLAEPT--- 200

  Fly   247 RTQSRLIIREPQVTDSGNYTCSASNTE 273
                 |.||.....|.|.|.|.|.|.|
  Fly   201 -----LRIRSVHRMDRGGYYCIAQNGE 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	26/110 (24%)
		Ig_3	193..271	CDD:404760	17/78 (22%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
Ama	NP_731114.2	I-set	33..143	CDD:254352	27/121 (22%)
		Ig	37..127	CDD:299845	22/101 (22%)
		IG_like	154..234	CDD:214653	19/81 (23%)
		IGc2	161..223	CDD:197706	18/74 (24%)
		I-set	254..330	CDD:254352
		IGc2	254..322	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810