DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and CG7166

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	56/218 - (25%)
Similarity:	85/218 - (38%)	Gaps:	38/218 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 INGDSKLDNNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWH 123
            |.|...|..|...:.:|.|..   ..|...|.:|.|..|.|||..:....:.|       |:...
  Fly    23 IGGSFILPENDPPTTAPKFLS---RGHLYKVIVGETIELPCKVQNLGSFVLLW-------RKGSS 77

  Fly   124 ILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEA 188
            :|::|....|.|:||.|:     ..:.|||..|:.:|.|.|.||:..... ......::::||..
  Fly    78 VLTAGHLKITRDQRFKIV-----GDYNLQINGVKTQDAGDYICQLGDQEN-RDQVHTVEILVPPT 136

  Fly   189 F--ILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGP---RT 248
            .  :..:|::....|||:.|.|....:|.|.  ::|.|.|               ...||   ..
  Fly   137 LRALPHNGQVTARKGSTVTLECKASGNPVPT--IFWFKKD---------------VFSGPTHLSD 184

  Fly   249 QSRLIIREPQVTDSGNYTCSASN 271
            .|.||:.......:|.|.|||.|
  Fly   185 SSTLILENVDRHHAGTYQCSADN 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	25/96 (26%)
		Ig_3	193..271	CDD:404760	21/80 (26%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/95 (26%)
		Ig	56..116	CDD:143165	20/71 (28%)
		IG_like	144..221	CDD:214653	22/81 (27%)
		IGc2	151..209	CDD:197706	21/74 (28%)
		IG_like	232..313	CDD:214653
		Ig	242..311	CDD:143165
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810