DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and dpr13

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	101/266 - (37%)
Similarity:	154/266 - (57%)	Gaps:	34/266 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LDNNLDSSD-----------SPMFEDSELMAHNTTV---QLGGTAFLVCKVSGVDRVGVNWNQIS 115
            ::|:|::::           :||:..:|    |:||   |:|.||.:.|.|..:.. ||    :|
  Fly   153 VENHLEANNGIEGGMESLFGTPMYFGTE----NSTVVTTQIGATAHVPCTVHHIGE-GV----VS 208

  Fly   116 WIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVST--PTGIISHF 178
            |||::|:|:|:.|...|::||||:..|...|..|||||||||.||.|:|||||||  ||.|   |
  Fly   209 WIRKKDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTSI---F 270

  Fly   179 VNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETT 243
            ::|.||...|.|.|....::..|||:.|.|.:.::....:|::|..::|:||| |..|.|.:.|.
  Fly   271 LHLSVVEARAEITGPPIRYLTPGSTLRLQCRVVQNTEASEYIFWYHDNRMINY-DIDRGINVSTE 334

  Fly   244 PGPRTQSRLIIREPQVTDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLT----HI 304
            |..:: |.|.|:..:...|||:||.||||:|||:.|.:.||||.||:.......:.:.|    |:
  Fly   335 PDFQS-SELTIQRTRREHSGNFTCVASNTQPASVLVHIFKGDNPAAMYHGHVGGSTKTTQSQLHM 398

  Fly   305 FRSMLA 310
            ...::|
  Fly   399 IMIIIA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	50/101 (50%)
		Ig_3	193..271	CDD:404760	25/77 (32%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	3/4 (75%)
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	51/107 (48%)
		IG_like	182..262	CDD:214653	41/84 (49%)
		IG_like	285..362	CDD:214653	26/78 (33%)
		IGc2	292..361	CDD:197706	25/70 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X190
	7	6.960