DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and CG13506

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	325	Identity:	63/325 - (19%)
Similarity:	107/325 - (32%)	Gaps:	129/325 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KSILTDNDWKKLWMRGGINGD-SKLDNN-----LDSSDSPMFEDSELMA---------------- 84
            ::.|.||...| |....:||. |.:||.     ||:.|.....|.:.:|
  Fly   191 RTYLPDNATIK-WSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDV 254

  Fly    85 ----------HNTTVQLGGTAFLVC--KVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDER 137
                      ||...:.|.||.|.|  :...:.|.               :.:..|..|..:| :
  Fly   255 QYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRS---------------YFIKDGKTLQLSD-K 303

  Fly   138 FAI---LHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGELHVD 199
            :::   :|. ..|..||.::.|...|.|.|.|||..                   .:||.|:.|.
  Fly   304 YSLKDSVHN-DHNRTTLIVREVTDSDLGEYLCQVEN-------------------AIGSNEVKVH 348

  Fly   200 MGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTD--- 261
                      :..:|..||:                .|:|:|   |.:.....::|..|:..
  Fly   349 ----------VSYNPETPQF----------------EDMTVE---GNKVTLHWLVRSHQLLSEAM 384

  Fly   262 -----SGNYTCSA---------SNTEPASIY-----VFVSKGDNMAAISRRKTSSADRLT--HIF 305
                 :|:||.|.         :||:  :|:     :.:|:|...|.:..:.|......:  |:|
  Fly   385 LDYQLTGSYTWSTVQVLETHRHNNTD--NIWKITHQLELSRGVWHARVKTKNTKGWSHFSNDHVF 447

Fly 306 305
Fly 448 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	21/101 (21%)
		Ig_3	193..271	CDD:404760	16/94 (17%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	0/3 (0%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653
		IGc2	83..146	CDD:197706
		IG_like	176..254	CDD:214653	15/63 (24%)
		Ig	176..239	CDD:299845	14/48 (29%)
		I-set	258..349	CDD:254352	26/136 (19%)
		Ig	275..348	CDD:143165	21/108 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900