DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr12 and Lac

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:197 Identity:60/197 - (30%)
Similarity:83/197 - (42%) Gaps:26/197 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 LGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKF 155
            :|||....|.|    :....:|.:......|...||:|:.|...|.||::.:.|.|:.:.||||.
  Fly    42 IGGTVEFDCSV----QYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKD 102

  Fly   156 VQRRDHGMYECQVSTPT-GIISHFVNLQVVVPEAFILGSGELHV-DMGSTINLVCIIEKSPTPPQ 218
            :|..|.|.|.|||...| ..:|..|.|.|..|......|.:..| ..||.:.:.|.....|||. 
  Fly   103 IQETDAGTYTCQVVISTVHKVSAEVKLSV
RRPPVISDNSTQSVVASEGSEVQMECYASGYPTPT- 166

  Fly   219 YVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSASNTEPASIYVFVSK 283
             :.|::.:..|...||      .|..|    :.|.|:..:..|.|.|.|.|.|.        |||
  Fly   167 -ITWRRENNAILPTDS------ATYVG----NTLRIKSVKKEDRGTYYCVADNG--------VSK 212

  Fly   284 GD 285
            ||
  Fly   213 GD 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 31/92 (34%)
Ig_3 193..271 CDD:404760 21/78 (27%)
Ig strand B 204..208 CDD:409353 0/3 (0%)
Ig strand C 219..223 CDD:409353 0/3 (0%)
Ig strand E 250..254 CDD:409353 1/3 (33%)
Ig strand F 264..269 CDD:409353 2/4 (50%)
LacNP_523713.2 IG_like 36..131 CDD:214653 31/92 (34%)
FR1 37..50 CDD:409353 3/7 (43%)
Ig strand A' 37..42 CDD:409353 60/197 (30%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 1/11 (9%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 5/13 (38%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/30 (43%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 22/85 (26%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/5 (0%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 60/197 (30%)
Ig 227..318 CDD:416386
Ig strand C 256..260 CDD:409353
Ig strand E 286..290 CDD:409353
Ig strand F 300..305 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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