DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and DIP-zeta

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	66/232 - (28%)
Similarity:	96/232 - (41%)	Gaps:	37/232 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GGINGDSKLDNNLD-SSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRR 120
            ||.|..:   :||: ..:.|.|.:   ...|.||..|....|.|.|..:...     :::|:...
  Fly    97 GGANVPT---SNLNIVVEEPEFTE---YIENVTVPAGRNVKLGCSVKNLGSY-----KVAWMHFE 150

  Fly   121 DWHILSSGAQLYTNDERFAILHTPGS--NMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQV 183
            ...||:....:.|.:.|.::.|....  ..|.|.|..|...|.|.|.||::|.|. .:.|..|.|
  Fly   151 QSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTA-KTQFGYLNV 214

  Fly   184 VVPEAF--ILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDR---LIN---YVDSRRDITI 240
            |||...  .|.|.::.|..|:.|:|.|....||.|  .:.|:::|.   .||   .|:.....|:
  Fly   215 VVPPNIDDSLSSSDVIVREGANISLRCRASGSPRP--IIKWKRDDNSRIAINKNHIVNEWEGDTL 277

  Fly   241 ETTPGPRTQSRLIIREPQVTDSGNYTCSASNTEPASI 277
            |.|    ..|||        |.|.|.|.|||..|.::
  Fly   278 EIT----RISRL--------DMGAYLCIASNGVPPTV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	26/98 (27%)
		Ig_3	193..271	CDD:404760	25/83 (30%)
		Ig strand B	204..208	CDD:409353	2/3 (67%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	3/3 (100%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	27/101 (27%)
		Ig	130..200	CDD:143165	17/74 (23%)
		I-set	226..310	CDD:254352	28/91 (31%)
		IGc2	233..298	CDD:197706	25/78 (32%)
		Ig	313..410	CDD:299845
		IG_like	325..410	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810