DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	60/213 - (28%)
Similarity:	95/213 - (44%)	Gaps:	19/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 NNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQL 131
            :.|::|| |.|...   .:|:||.:|..|.|.|.|.  |.|..   :::|:|.....|||....:
  Fly    24 SELNNSD-PKFSGP---INNSTVPVGRDALLTCVVH--DLVSF---KVAWLRVDTQTILSIQNHV 79

  Fly   132 YTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFI--LGSG 194
            .|.:.|.:|.||. ..:|.|:|:.||..|.|.|.||::|.. :.|....|.||||...:  ..|.
  Fly    80 ITKNHRISISHTE-HRIWQLKIRDVQESDRGWYMCQINTDP-MKSQMGYLDVVVPPDIVDYQTSQ 142

  Fly   195 ELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQV 259
            ::....|..:.|.|.....|.|.  :.|::.:.....:....|..:.:..|    ..|.:.:.|.
  Fly   143 DVVRSTGQNVTLTCSATGVPMPT--ITWRREEATPILISDDGDREVFSVEG----QNLTLWQVQR 201

  Fly   260 TDSGNYTCSASNTEPASI 277
            :..|.|.|.|||..|.::
  Fly   202 SHMGAYLCIASNGVPPTV 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	33/96 (34%)
		Ig_3	193..271	CDD:404760	15/77 (19%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	32/92 (35%)
		Ig	39..122	CDD:299845	31/89 (35%)
		Ig	132..213	CDD:299845	16/86 (19%)
		IG_like	141..227	CDD:214653	18/85 (21%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810