DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr12 and CG33543

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	197	Identity:	46/197 - (23%)
Similarity:	69/197 - (35%)	Gaps:	53/197 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 SNMWTLQIKFVQRRDHGMYECQVS-TPTGIISHFVNLQVVVPEAFILGSGELHVDM--------- 200
            :.:..|..:.:...|.|.:.|:|: ...|      |..|.|...| |.|.||.|:.
  Fly   102 TGLLALVFEHIALEDRGNWTCEVNGNRNG------NRNVNVEREF-LASFELLVNQKISFGKTEQ 159

  Fly   201 ------GSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQV 259
                  |....:.|.:|..|.|.  |.|..|...||        |:.:|...|..:.|.||....
  Fly   160 VQSVREGRDAMVNCFVEGMPAPE--VSWLYNGEYIN--------TVNSTKHNRLSNGLYIRNVSQ 214

  Fly   260 TDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTHIFRSMLAPCLLLN-TVVVRHI 323
            .|:|.|||.|....|.                   .|.:|::|.:.|....|....| |:.|::.
  Fly   215 ADAGEYTCRAMRITPT-------------------FSDSDQITILLRIQHKPHWFFNETLPVQYA 260

  Fly   324 FL 325
            ::
  Fly   261 YV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	7/37 (19%)
		Ig_3	193..271	CDD:404760	26/92 (28%)
		Ig strand B	204..208	CDD:409353	0/3 (0%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	1/3 (33%)
		Ig strand F	264..269	CDD:409353	3/4 (75%)
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	21/68 (31%)
		IG_like	256..336	CDD:214653	1/7 (14%)
		IGc2	263..327	CDD:197706	46/197 (23%)
		FN3	341..445	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900