DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr12 and Opcml

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:249 Identity:64/249 - (25%)
Similarity:97/249 - (38%) Gaps:72/249 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 NGDSKLDNNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHI 124
            :||:.....:|               |.||:.|.:|.|.|.:.  |||    .:::|:.|..  |
Mouse    33 SGDATFPKAMD---------------NVTVRQGESATLRCTID--DRV----TRVAWLNRST--I 74

  Fly   125 LSSGAQLYTNDERFAIL-HTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEA 188
            |.:|...::.|.|..|| :||  ..:::.|:.|...|.|.|.|.|.|.....:..|:|.|.||..
Mouse    75 LYAGNDKWSIDPRVIILVNTP--TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ 137

  Fly   189 FILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQ-----------KNDRLINYVDSRRDITIET 242
            .:..|.::.|:.||::.|:|:....|.|.  |.|:           ..|..:...|.:||     
Mouse   138 IMNISSDITVNEGSSVTLLCLAIGRPEPT--VTWRHLSVKEGQGFVSEDEYLEISDIKRD----- 195

  Fly   243 TPGPRTQSRLIIREPQVTDSGNYTCSASNTEPA------SIYV----FVSKGDN 286
                              .||.|.|||.|...|      .|.|    ::||..|
Mouse   196 ------------------QSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKN 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 31/97 (32%)
Ig_3 193..271 CDD:404760 20/88 (23%)
Ig strand B 204..208 CDD:409353 1/3 (33%)
Ig strand C 219..223 CDD:409353 1/3 (33%)
Ig strand E 250..254 CDD:409353 0/3 (0%)
Ig strand F 264..269 CDD:409353 2/4 (50%)
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 31/97 (32%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/5 (20%)
FR2 64..70 CDD:409353 1/5 (20%)
Ig strand C 64..70 CDD:409353 1/5 (20%)
CDR2 71..83 CDD:409353 4/13 (31%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 12/35 (34%)
Ig strand D 87..94 CDD:409353 3/6 (50%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 135..206 CDD:404760 21/95 (22%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 2/6 (33%)
Ig strand C' 171..174 CDD:409353 0/2 (0%)
Ig strand F 198..206 CDD:409353 5/7 (71%)
Ig_3 223..300 CDD:404760 3/9 (33%)
putative Ig strand A 224..230 CDD:409353 2/5 (40%)
Ig strand B 240..244 CDD:409353
Ig strand C 253..257 CDD:409353
Ig strand E 279..283 CDD:409353
Ig strand F 293..298 CDD:409353
Ig strand G 306..309 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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