DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr12 and Lrit1

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:229 Identity:47/229 - (20%)
Similarity:78/229 - (34%) Gaps:50/229 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 EDSELMAHNTTV--QLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAI 140
            :..||....|::  .||.|..|.|..:|:....::|.:            ::|..|  |......
Mouse   253 QSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRR------------ANGRPL--NGTVHQE 303

  Fly   141 LHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGELHVDMGST-- 203
            :.:.||:...|.:..|...|.|.|.||.....|.....::|.|..|:.....||...|....|  
Mouse   304 VSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTGYSGIPGVLWARTGE 368

  Fly   204 ------INLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPG-PRTQSRLIIREPQVTD 261
                  .|...:....|..|::|                  .:.|.|. |..:..|.::..|:..
Mouse   369 GAEAAAYNNKLVARHVPHMPEHV------------------ALATKPSMPSIKEELALQNFQMDV 415

  Fly   262 SGNYTCSASNTEPA----SIYVFVSKGDNMAAIS 291
            .|.::...|..:.|    |:.|.   ||...::|
Mouse   416 PGEFSREPSEHQEAQMVRSLKVV---GDTYHSVS 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 22/98 (22%)
Ig_3 193..271 CDD:404760 14/86 (16%)
Ig strand B 204..208 CDD:409353 1/3 (33%)
Ig strand C 219..223 CDD:409353 1/3 (33%)
Ig strand E 250..254 CDD:409353 1/3 (33%)
Ig strand F 264..269 CDD:409353 0/4 (0%)
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..>176 CDD:290566
LRR_4 131..172 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>241 CDD:301599
Ig 258..346 CDD:299845 22/101 (22%)
IG_like 268..346 CDD:214653 21/91 (23%)
FN3 432..502 CDD:214495 5/18 (28%)
LRR 6 526..549
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.