DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr12 and Iglon5

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:295 Identity:70/295 - (23%)
Similarity:104/295 - (35%) Gaps:106/295 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 LDNNLDSSDSPMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGA 129
            |..:|:.| ||        |.|.||..|..|.|.|.:.  :.|    .:::|:.|.  :||.:|.
Mouse    29 LSQSLEFS-SP--------ADNYTVCEGDNATLSCFID--EHV----TRVAWLNRS--NILYAGN 76

  Fly   130 QLYTNDERFAIL-HTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGS 193
            ..:|:|.|..:| :||  ..:::.|..|...|.|:|.|...|.....:..|.|.|.||...:..|
Mouse    77 DRWTSDPRVRLLINTP--EEFSILITQVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS 139

  Fly   194 GELHVDMGSTINLVC------------------------IIEKS--------------------- 213
            ..:.|:.|..:||:|                        |:|.|                     
Mouse   140 SPVAVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204

  Fly   214 -------------PT------------------------PPQYVYWQKNDRLINYVDSRRDITIE 241
                         ||                        ||....|.|:|||:: ..|...:.::
Mouse   205 PDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS-SGSAEGLKVQ 268

  Fly   242 TTPGPRTQSRLIIREPQVTDSGNYTCSASNTEPAS 276
            |   .||:|.|:.........|||||.|:|...||
Mouse   269 T---ERTRSMLLFANVSARHYGNYTCRAANRLGAS 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 28/97 (29%)
Ig_3 193..271 CDD:404760 30/159 (19%)
Ig strand B 204..208 CDD:409353 2/3 (67%)
Ig strand C 219..223 CDD:409353 0/3 (0%)
Ig strand E 250..254 CDD:409353 2/3 (67%)
Ig strand F 264..269 CDD:409353 4/4 (100%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 28/97 (29%)
Ig strand A' 41..46 CDD:409353 3/4 (75%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/5 (0%)
FR2 61..68 CDD:409353 1/6 (17%)
Ig strand C 61..67 CDD:409353 1/5 (20%)
CDR2 69..79 CDD:409353 3/11 (27%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 12/36 (33%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/8 (25%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A 132..137 CDD:409353 1/4 (25%)
Ig_3 134..199 CDD:404760 9/64 (14%)
Ig strand A' 140..145 CDD:409353 0/4 (0%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 2/4 (50%)
Ig strand F 191..199 CDD:409353 0/7 (0%)
Ig_3 217..295 CDD:404760 21/81 (26%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 70/295 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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