DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and zig-4

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	114	Identity:	27/114 - (23%)
Similarity:	46/114 - (40%)	Gaps:	30/114 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 TGIISHFVNLQVVVP-EAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKN---------- 225
            |..::....:::|.| |:.::..||       |..|.|.|  ..||...::|:.|
Worm    37 TNYLTSPAKIKIVAPLESALIPGGE-------TYQLRCDI--MSTPAATIHWKFNGKLIQGSNEL 92

  Fly   226 ---DRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGNYTCSASN 271
               ::|:|:..:..|..|       ..|.|.|:.|...:||.|:|...|
Worm    93 NVEEKLLNFGKAIVDTGI-------VASILTIQCPSAENSGTYSCVGYN 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	1/10 (10%)
		Ig_3	193..271	CDD:404760	22/90 (24%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	26/104 (25%)
		Ig	65..144	CDD:143165	20/79 (25%)
		IG_like	176..245	CDD:214653
		Ig	<193..238	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900