DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and Kirrel

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	200	Identity:	51/200 - (25%)
Similarity:	79/200 - (39%)	Gaps:	42/200 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 TVQLGGTAFLVC---KVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMW 149
            ||..|..|.|.|   ..||:    |.|.       :|...|..|..|.. ..|:.::.:..:..:
Mouse    63 TVVAGQRAVLPCVLLNYSGI----VQWT-------KDGLALGMGQGLKA-WPRYRVVGSADAGQY 115

  Fly   150 TLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVP--EAFILGSGELHVDMGSTINLVCIIEK 212
            .|:|...:..|...|||| :|...:.|....|.|::|  |..|.|...:.:..|:..||.|....
Mouse   116 NLEITDAELSDDASYECQ-ATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFN 179

  Fly   213 SPTPPQYVYWQK----------NDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTDSGN-YT 266
            : .|...:.|.:          :..|:.  |.:|:.||         |:|:| ||...|.|. :|
Mouse   180 A-KPAATIIWFRDGTQQEGAVTSTELLK--DGKRETTI---------SQLLI-EPTDLDIGRVFT 231

  Fly   267 CSASN 271
            |.:.|
Mouse   232 CRSMN 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	25/97 (26%)
		Ig_3	193..271	CDD:404760	20/88 (23%)
		Ig strand B	204..208	CDD:409353	2/3 (67%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/5 (40%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	25/97 (26%)
		Ig2_KIRREL3-like	170..251	CDD:143236	19/79 (24%)
		Ig	255..336	CDD:386229
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810