DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and ntm

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	69/315 - (21%)
Similarity:	105/315 - (33%)	Gaps:	123/315 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 NTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWT 150
            |.||:.|.:|.|.|.|.  :||    .:::|:.|..  ||.:|...::.|.|..:|....| .::
Frog    45 NVTVRQGDSAILRCTVD--NRV----TRVAWLNRST--ILYTGNDKWSIDPRVVLLANTKS-QYS 100

  Fly   151 LQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGELHVDMGSTINLVCIIEKSPT 215
            ::|:.|...|.|.|.|.|.|.....:..|:|.|.||...:..|..:.|:.||.::|:||....|.
Frog   101 IEIQNVDIYDEGPYTCSVQTDNHPKTSRVHLIVQVPPRIVDISSSIAVNEGSNVSLICIANGRPE 165

  Fly   216 P--------------------------------------------------------PQYV---- 220
            |                                                        |.|:
Frog   166 PVVNWRYLSPKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYILDAQ 230

  Fly   221 ------------------------YWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVTD 261
                                    :|.|.|:.::  ||.|.:.:|..   .|.||:........|
Frog   231 NIGAPLGHRGILQCEASAVPAADFFWYKEDKRLS--DSWRGVKVENR---ETISRVTFLNVSEQD 290

  Fly   262 SGNYTCSASNT---EPASIYVFVSKGDNMAAISRRKTSSADRLTHIFRSMLAPCL 313
            .|||||.|.|.   ..|||.:|                      .:|:|..:|.|
Frog   291 YGNYTCMAKNLLGHSNASIILF----------------------ELFQSTSSPLL 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	29/96 (30%)
		Ig_3	193..271	CDD:404760	28/161 (17%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	1/31 (3%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	4/4 (100%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	29/96 (30%)
		IG_like	45..133	CDD:214653	29/96 (30%)
		IG_like	143..220	CDD:214653	9/76 (12%)
		IGc2	150..209	CDD:197706	7/58 (12%)
		ig	227..311	CDD:278476	21/88 (24%)
		IG_like	230..311	CDD:214653	21/85 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000