DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr12 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	315	Identity:	57/315 - (18%)
Similarity:	97/315 - (30%)	Gaps:	111/315 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 TLLLATTLEPDQKSILTDNDWKKLWMRGGINGDSKLD--------NNLDSSDSPMF--------- 77
            ||.|..|.:.:..:.:.       |:..|:|..|...        |||:..:|..:
Zfish   245 TLTLTCTADSNPPATIQ-------WVFNGVNLPSNAVSSPANFTLNNLEEKNSGNYTCVAYNAQT 302

  Fly    78 ------------------------EDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIR 118
                                    ..|.|:|.|:||.|  |.|     :...|.    ..:.|:
Zfish   303 KRYIASRVAFVTVVESLSGTNISSSTSLLIAGNSTVNL--TCF-----AAAGRA----ETVEWV- 355

  Fly   119 RRDWHILSSGAQLYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQV 183
             :|...|:..:::..:.::.::           .|..|.:.|.|.|.|.:...........||::
Zfish   356 -KDGKPLNPDSRIVFSADKTSV-----------SIDKVVKEDRGEYRCLLRNKVNKDEASYNLKI 408

  Fly   184 VVPEAFILGSGELHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRT 248
            ......:...|:..|.....:.|.|..|.  .||....|:.|...:|                .:
Zfish   409 NYGPEKVAVQGKHAVKFEDDVELSCTAES--VPPSTYTWKLNGTALN----------------SS 455

  Fly   249 QSRLIIREPQVTDSGNYTCSASNTEPASIYVFVSKGDNMAAISRRKTSSADRLTH 303
            |...:::..:..|||.|||.|.|              |:       |...|:.||
Zfish   456 QQVYVVKRAKDRDSGIYTCEAFN--------------NI-------TGKMDKTTH 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr12	NP_652462.3	IG	86..183	CDD:214652	18/96 (19%)
		Ig_3	193..271	CDD:404760	18/77 (23%)
		Ig strand B	204..208	CDD:409353	1/3 (33%)
		Ig strand C	219..223	CDD:409353	0/3 (0%)
		Ig strand E	250..254	CDD:409353	0/3 (0%)
		Ig strand F	264..269	CDD:409353	3/4 (75%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845
		IG_like	33..128	CDD:214653
		Ig	130..222	CDD:299845
		IG_like	149..222	CDD:214653
		I-set	233..315	CDD:254352	12/76 (16%)
		Ig_2	235..315	CDD:290606	12/76 (16%)
		IGc2	335..398	CDD:197706	16/86 (19%)
		Ig_2	427..494	CDD:290606	22/102 (22%)
		IG_like	427..479	CDD:214653	17/83 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910