DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr12 and negr1

DIOPT Version :9

Sequence 1:NP_652462.3 Gene:dpr12 / 50320 FlyBaseID:FBgn0085414 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:274 Identity:63/274 - (22%)
Similarity:100/274 - (36%) Gaps:92/274 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 NTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQLYTNDERFAILHTPGSNMWT 150
            |..|:.|.||.|.|.:......|      :|:.|..  |:.:|...::.|.|.:|. |.....::
 Frog    48 NLVVRQGETAMLRCFLEEGASKG------AWLNRSS--IIFAGGDKWSVDPRVSIA-TSSKQEYS 103

  Fly   151 LQIKFVQRRDHGMYECQVSTPTGIISHFVNLQV-VVPEAFILGSGELHVDMGSTINLVCIIEKSP 214
            |:|:.|...|.|.|.|.|.|.....:..|:|.| |.|:.:.: |.::.|:.|:.::|:|:....|
 Frog   104 LRIQKVDVSDDGPYTCSVQTEHSPRTLQVHLTVHVSPKIYDI-SSDMTVNEGTNVSLICLATGKP 167

  Fly   215 TPP----------------QY--VYWQKNDRLINY-VDSRRDIT-----------------IETT 243
            .|.                ||  :|....|:..:| ..:..|::                 :|.|
 Frog   168 EPSISWRHISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDVSFPDVKKVKVTVNFAPTILEIT 232

  Fly   244 P-------------------------------------GPRTQ---SRLIIREPQVTDS--GNYT 266
            |                                     |.|.|   :|.|:....||:.  ||||
 Frog   233 PTGVSLGRTGLIRCETAAVPAPVFEWYKGEKKLTNGQRGIRIQNYNTRSILTVSNVTEEHFGNYT 297

  Fly   267 CSASN---TEPASI 277
            |.|.|   |..||:
 Frog   298 CVAVNKLGTSNASL 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr12NP_652462.3 IG 86..183 CDD:214652 27/96 (28%)
Ig_3 193..271 CDD:404760 29/155 (19%)
Ig strand B 204..208 CDD:409353 1/3 (33%)
Ig strand C 219..223 CDD:409353 2/5 (40%)
Ig strand E 250..254 CDD:409353 1/3 (33%)
Ig strand F 264..269 CDD:409353 4/4 (100%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 27/96 (28%)
FR1 44..62 CDD:409353 6/13 (46%)
Ig strand A' 47..53 CDD:409353 2/4 (50%)
Ig strand B 55..63 CDD:409353 4/7 (57%)
CDR1 63..68 CDD:409353 0/4 (0%)
FR2 69..75 CDD:409353 2/11 (18%)
Ig strand C 69..74 CDD:409353 2/10 (20%)
CDR2 76..87 CDD:409353 2/12 (17%)
Ig strand C' 78..82 CDD:409353 1/3 (33%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 11/34 (32%)
Ig strand D 91..98 CDD:409353 3/7 (43%)
Ig strand E 101..107 CDD:409353 1/5 (20%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 1/3 (33%)
Ig strand G 127..136 CDD:409353 2/8 (25%)
FR4 129..136 CDD:409353 2/6 (33%)
Ig_3 140..208 CDD:404760 13/68 (19%)
Ig strand A' 146..151 CDD:409353 1/4 (25%)
Ig strand B 157..164 CDD:409353 2/6 (33%)
Ig strand C 170..175 CDD:409353 0/4 (0%)
Ig strand C' 177..179 CDD:409353 0/1 (0%)
Ig strand E 187..193 CDD:409353 2/5 (40%)
Ig strand F 200..207 CDD:409353 1/6 (17%)
Ig strand G 214..222 CDD:409353 0/7 (0%)
Ig_3 226..302 CDD:404760 16/75 (21%)
putative Ig strand A 226..232 CDD:409353 1/5 (20%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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