Protein Alignment CG32354 and agrn

DIOPT Version :10

• Sequence 1: NP_729380.1
• Gene: CG32354 / 50302
• FlyBaseID: FBgn0052354
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_021325504.1
• Gene: agrn / 565373
• ZFINID: ZDB-GENE-030131-1033
• Length: 2056
• Species: Danio rerio
• Alignment Length: 650
• Identity: 180/650 - (27%)
• Similarity: 247/650 - (38%)
• Gaps: 216/650 - (33%)

  Fly   178 PVCGSDGLIYANICELRKKTCS--------RSGVSLIKDVRDGCERSKGSDC---------KHRC 225
            ||||||...|:|.|||.|..|:        |.|...:||.......|.||.|         |..|
Zfish   212 PVCGSDSSTYSNECELEKAQCNTQRRIKVMRKGPCALKDPCSEVTCSFGSTCIQSSDGLSAKCMC 276

  Fly   226 --STEKDP---VCGTDGRTYLNRCMLRVQSCRVGLAAVKLSHVG---PCSNT-----SAVR---- 273
              |.|..|   |||:||..|.:.|.|.:::|.. ...:::.|.|   |||:|     :|.|
Zfish   277 PLSCENVPKHVVCGSDGLDYQSECELNMKACAT-QKNIRVHHQGRCDPCSDTLNSLSTACRVNPK 340

  Fly   274 ----------ESCPVDCNSAPKDGPVCSSDGNVYNSTCEM---------KLKTCGQGVVKTS--- 316
                      ||||      |.:.|:|:|||:.|.|.|:|         :||....|..|..
Zfish   341 TYQQITFAPAESCP------PDEMPICASDGHTYESMCQMERTALKNNLELKKVSLGSCKEKGGC 399

  Fly   317 RKHCQSTRMC-------RESCWRVA-----RPTCGSDGRLYASPCKMRSSNCGKHVFEVPL---- 365
            ...|:...:|       |.||..:.     :|.||.||:.|.:.|:.:...| :...::|:
Zfish   400 PNGCKFNAICLLDNGEFRCSCDPIQCDGTYKPLCGKDGKTYPNDCERKLQEC-RTQKDIPVKQQG 463

  Fly   366 -------SYCMSQE-RHGA-------------SDACPTECPKSDTDSSSQYVCGSDGNIYSSLCE 409
                   |.|:.:. ..||             |||||     .|.|.    ||||||:.|||.|:
Zfish   464 PCDLNLESPCLKKTCEFGAVCVVKNSEAVCECSDACP-----QDQDP----VCGSDGHTYSSSCQ 519

  Fly   410 LKMLNCGPQRKSIQKVSMDKCKNRLTRCKQLPPCKD---FNSLFGSIFSS------------KRN 459
            :|.:.|..| |.||             .:...||.|   .|..||:|..:            :..
Zfish   520 MKAMGCALQ-KQIQ-------------MQHKGPCADESCTNCSFGAICDAQTGRCVCPKGCLETR 570

  Fly   460 DKLCGTDAKTYNNECELAHATCLRGVNL---AHIGPCTDLNSPTKDCGDACTRADLEQQ------ 515
            ..:||:|..||:|||:|....|.:.::|   || |.|....|.....|..|.....|.|
Zfish   571 QPVCGSDGTTYDNECKLNVQACTKQLDLKVVAH-GECKTCGSTVCSWGSQCVNNKCECQQCTGQP 634

  Fly   516 --PVCGSDGNTFASMCEFKRRTCD-LRVVPVSL-----KNCAL--------------------TA 552
              |||||||||:.:.||.:..:|. .|.:.|:.     ::|..                    |.
Zfish   635 VKPVCGSDGNTYNNDCELRLASCQKQRKIEVAKPGVCDEDCGSGGSGSGSETCEQDRCRRYGGTW 699

  Fly   553 D---------CESDCDAQPPSFVCGSDNNLYKSECHMRKENCGKHVFVVPLKRCLAAFQLKGCAR 608
            |         ||.:|.....|.|||||.|.|.|:|.::|..|.|.:.:        :.|.:|
Zfish   700 DDDMEDERCVCELNCQIVLHSPVCGSDGNTYSSDCELKKTRCEKQIDL--------SVQSQG--- 753

  Fly   609 ICPREFEPV---------------CGSDNKTYLNDCFLEIENCRANQTVNVNYYGACGRPEAPST 658
            .||....|.               |..||||    ..|.:...........|:||:.|....|||
Zfish   754 PCPTIVSPPPELVASQHCSQTVYGCCEDNKT----AALGVGLAGCPSMCQCNHYGSYGGTCDPST 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:412159	13/29 (45%)
		KAZAL	220..266	CDD:197624	17/62 (27%)
		KAZAL_FS	326..>359	CDD:412159	12/44 (27%)
		KAZAL	380..430	CDD:197624	20/49 (41%)
		KAZAL	452..493	CDD:197624	15/55 (27%)
		KAZAL	502..>536	CDD:197624	15/41 (37%)
		KAZAL_FS	553..597	CDD:412159	17/52 (33%)
		KAZAL	606..650	CDD:197624	12/58 (21%)
agrn	XP_021325504.1	NtA	43..146	CDD:460825
		KAZAL	200..246	CDD:197624	15/33 (45%)
		KAZAL	276..321	CDD:197624	15/45 (33%)
		KAZAL_FS	353..393	CDD:238052	15/45 (33%)
		KAZAL	422..465	CDD:197624	9/43 (21%)
		KAZAL	494..539	CDD:197624	23/67 (34%)
		KAZAL	561..606	CDD:197624	14/45 (31%)
		KAZAL	626..671	CDD:197624	16/44 (36%)
		KAZAL	709..755	CDD:197624	18/56 (32%)
		Laminin_EGF	798..840	CDD:395007	6/16 (38%)
		Laminin_EGF	852..>888	CDD:395007
		KAZAL	932..974	CDD:197624
		SEA	1131..1228	CDD:470595
		EGF	1328..1356	CDD:394967
		LamG	1369..1519	CDD:238058
		Laminin_G_1	1663..1794	CDD:395008
		EGF_CA	1814..1845	CDD:238011
		Laminin_G_1	1908..2039	CDD:395008