DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32354 and fstl3

DIOPT Version :9

Sequence 1:	NP_729380.1	Gene:	CG32354 / 50302	FlyBaseID:	FBgn0052354	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001015870.1	Gene:	fstl3 / 548587	XenbaseID:	XB-GENE-876426	Length:	255	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	81/353 - (22%)
Similarity:	110/353 - (31%)	Gaps:	132/353 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 SITVGAEPVCGSDGLIYANICELRK---KTCSRSGVSLIKDVRDGCERSKGSDCKHRCSTE---K 229
            ::|.| .|:.|.|.|.....|.|.:   .||||..:|.:  ..|.|.:....|......||   |
Frog    13 TVTRG-HPIPGGDTLQSGGTCWLLQGTDSTCSRMLLSSV--TWDECCKDGHIDTAWSNYTEPMNK 74

  Fly   230 DPVCGTDGRTYLNRCMLRVQSCRVGLAAVKLSHVGPCSNTSAVRE-----SCPVDCNSAPKDGPV 289
            ..:.|..|       ::..|.||.....|:.    |...|..:::     .|..||:....|.||
Frog    75 ISLLGFLG-------LVSCQPCRDSCEGVQC----PPGKTCFLKDGRPQCECTPDCSGLEADVPV 128

  Fly   290 CSSDGNVYNSTCEMKLKTCGQGVVKTSRKHCQSTRM----CRESCWRVARPTCGSDGRLYASPCK 350
            |.|||:.|...||:..|.|        |.|.....|    |::||..|..|
Frog   129 CGSDGHTYQDECELVTKKC--------RGHPDLEVMYYGKCKKSCSNVVCP-------------- 171

  Fly   351 MRSSNCGKHVFEVPLSYCMSQERHGASDACPTECPKSDTDSSSQYVCGSDGNIYSSLCELKMLNC 415
                  |.|                       .|....|.|:...||
Frog   172 ------GTH-----------------------SCVVDQTGSAHCVVC------------------ 189

  Fly   416 GPQRKSIQKVSMDKCKNRLTRCKQLPPCKDFNSLFGSIFSSKRNDKLCGTDAKTYNNECELAHAT 480
                             |.|.|.|  |.     .||::        |||.:..||.:.|.|..||
Frog   190 -----------------RSTPCPQ--PL-----AFGNM--------LCGNNNVTYPSACHLRRAT 222

  Fly   481 CLRG--VNLAHIGPCTDLNSPTKDCGDA 506
            |..|  :.:.|.|.|.|:...:.|..|:
Frog   223 CYLGKSIGVRHTGSCADIPEFSMDLDDS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:294071	10/31 (32%)
		KAZAL	220..266	CDD:197624	10/48 (21%)
		KAZAL_FS	326..>359	CDD:294071	6/32 (19%)
		KAZAL	380..430	CDD:197624	5/49 (10%)
		KAZAL	452..493	CDD:197624	13/42 (31%)
		KAZAL	502..>536	CDD:197624	2/5 (40%)
		KAZAL_FS	553..597	CDD:294071
		KAZAL	606..650	CDD:197624
fstl3	NP_001015870.1	KAZAL	<127..161	CDD:197624	14/41 (34%)
fstl3	NP_001015870.1	KAZAL_FS	205..237	CDD:238052	12/31 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I12193
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000