DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32354 and CG1077

DIOPT Version :9

Sequence 1:NP_729380.1 Gene:CG32354 / 50302 FlyBaseID:FBgn0052354 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_649617.1 Gene:CG1077 / 40751 FlyBaseID:FBgn0037405 Length:730 Species:Drosophila melanogaster


Alignment Length:516 Identity:95/516 - (18%)
Similarity:163/516 - (31%) Gaps:208/516 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 PVCG---SDGL--IYANICELRKKTCSRSGVSLIKDVRDGCERSKGSDCKHRCSTEKDPVCGT-- 235
            |.|.   .:|:  ::||.|:|||   ::.|..:...:.|...|.....|:..||:...||||.  
  Fly    37 PACAQSRENGMYFLFANECDLRK---AQRGNLMNGPLYDVTLRFCFPSCEFECSSRYQPVCGISS 98

  Fly   236 ---DGRTYLNRCMLRVQSCRVGLAAVKLSHVGPCSNTSAV-----RESCPVDCNSAPKDGPVCSS 292
               :.:|:.:||.:...:| :..:...:...|.|...:||     :...||.|.           
  Fly    99 KSGERKTFRSRCEMLRTAC-ISRSEWMVHRWGVCPKANAVPQISEKPPVPVPCT----------- 151

  Fly   293 DGNVYNSTCEMKLKTCGQGVVKTSRKHC--QSTRMCRESCWR-VARPTCGSDGRLYASPCKMRSS 354
              .:|...|.|.     .||..|....|  .:..:..:..|| |:...||.|.      .||:.|
  Fly   152 --RIYRPVCAMY-----AGVKSTFSNECLVNAENIKSQRNWRIVSEGLCGEDS------TKMKHS 203

  Fly   355 NCGKHVFEVPLSYCMSQERHGASDACPTECPKSDTDSSSQYVCGSDGNIYSSLCELKMLNCGPQR 419
            ...|                      |...||||.:.:.:...|                   :|
  Fly   204 RKQK----------------------PKAKPKSDAERTKRSHRG-------------------KR 227

  Fly   420 KSIQKVSMDKCKNRLTRCKQLPPCKDFN-----------SLFGSIFSSKRNDKLCGTDAKTYNNE 473
            .|.|                   .:||.           |.|.:.|.|:     .|...|:|:..
  Fly   228 LSTQ-------------------AEDFQIPEDAVEIYAPSTFHTQFISQ-----SGAMEKSYSLP 268

  Fly   474 CELAHATCLRGVNLAHIGPCTDLNSPTKDC--GDACTRADLEQQPVCGS---DGNTFASMC---E 530
            ....:..         :.|.:....|||.|  |:         :||||:   ...||:::|   |
  Fly   269 ARKPYVV---------VPPKSKRRIPTKSCVFGN---------EPVCGNLRGQSRTFSNVCELME 315

  Fly   531 FKRRTCDLRVVPVSLKNCALTADCESDCDAQPPSFVCGSDNNLYKSECHMRKENCGKHVFVVPLK 595
            |.::..:...:                               .:...|                 
  Fly   316 FSQKVGNAWTI-------------------------------AHNGAC----------------- 332

  Fly   596 RCLAAFQLKGCARICPREFEPVCGSD---NKTYLNDCFLEIENCRANQTV-NVNYYGACGR 652
                    :.|.:.||..::|:|.:.   |.|.:|:|:||...|:..::: .:::.|.|.:
  Fly   333 --------RRCDKTCPTVYQPICATRNGINHTIVNECYLERVRCKDPKSIWKLSHKGECAK 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32354NP_729380.1 KAZAL_FS 163..>200 CDD:294071 9/26 (35%)
KAZAL 220..266 CDD:197624 12/50 (24%)
KAZAL_FS 326..>359 CDD:294071 9/33 (27%)
KAZAL 380..430 CDD:197624 9/49 (18%)
KAZAL 452..493 CDD:197624 5/40 (13%)
KAZAL 502..>536 CDD:197624 11/41 (27%)
KAZAL_FS 553..597 CDD:294071 1/43 (2%)
KAZAL 606..650 CDD:197624 13/47 (28%)
CG1077NP_649617.1 KAZAL_FS 86..131 CDD:238052 11/45 (24%)
KAZAL_FS 149..193 CDD:294071 11/61 (18%)
KAZAL 335..383 CDD:197624 13/47 (28%)
Podoplanin <612..688 CDD:283467
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10913
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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