DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32354 and fstl1b

DIOPT Version :9

Sequence 1:	NP_729380.1	Gene:	CG32354 / 50302	FlyBaseID:	FBgn0052354	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001034710.1	Gene:	fstl1b / 324309	ZFINID:	ZDB-GENE-030131-3029	Length:	310	Species:	Danio rerio

Alignment Length:	376	Identity:	77/376 - (20%)
Similarity:	130/376 - (34%)	Gaps:	116/376 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 IYANIC-------ELRKKTCSR--SGVSLIKDVRDGCERSKGSD---CKHRCSTEKDPVCGTDGR 238
            :.|.:|       :.:.|.|:.  .|..     |:.....||..   |..:|.|.|..|||::|:
Zfish    11 LLAVVCCHAEQEAQSKSKVCANVFCGAG-----RECAVNEKGEPSCLCIEQCKTHKRSVCGSNGK 70

  Fly   239 TYLNRCMLRVQSCRVGLAAVKLSHVGPCSNTSAVRESC-PVDCNSAPKDGPVCSSDGNVYNSTCE 302
            ||.|.|.|...:|..|| .::::|.|.|......:.:. ||.|..|.::               |
Zfish    71 TYRNHCELHRDACLTGL-KIQVAHDGHCKEKKKEKAAASPVVCYVADRN---------------E 119

  Fly   303 MKLKTCGQGVVKTSRKHCQSTRMCRESCWRVARPTCGSDGRLYASPCKMRSSNCGKHVFEVPLSY 367
            ::.:     |::                |  .:.....||..          ..|.:..::.|.|
Zfish   120 LRRR-----VIE----------------W--LQTEVVPDGWF----------TKGSNFTDILLKY 151

  Fly   368 CMSQERHGASDACPTECPK----SDTD-SSSQYVCGSDGNIYSSLCELKMLNCGPQRKSIQKVSM 427
            ..:.: :|.|.....|..|    ::|. ..|.|....:..:..|||...::....:... .|:|.
Zfish   152 FKNYD-NGDSQLDSAELLKFIQHNETAVQMSSYAEEENNRLLRSLCVDALIELSDENAD-WKLSF 214

  Fly   428 DKCKNRLTRCKQ---LPPCKDFNSLFGSIFSSKRNDKLCGTDAKTYNNECELAHATCLRGVNLAH 489
            |:..|    |.:   .||                 :|.|..:.:||.:..| ....|.|.|
Zfish   215 DEFLN----CLKPGFSPP-----------------EKKCALEDETYEDGAE-TQVECNRCV---- 253

  Fly   490 IGPCTDLNSPTKDCGD-ACTRADL-EQQPVCGSDGNTFASMCEFKRRTCDL 538
               |.        ||: .||.... |:.||..::|:...:..|:.||..:|
Zfish   254 ---CA--------CGNWVCTAMTCDEKTPVFDTEGDQEMTEEEWTRRVAEL 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:294071	4/20 (20%)
		KAZAL	220..266	CDD:197624	18/48 (38%)
		KAZAL_FS	326..>359	CDD:294071	4/32 (13%)
		KAZAL	380..430	CDD:197624	11/54 (20%)
		KAZAL	452..493	CDD:197624	8/40 (20%)
		KAZAL	502..>536	CDD:197624	11/35 (31%)
		KAZAL_FS	553..597	CDD:294071
		KAZAL	606..650	CDD:197624
fstl1b	NP_001034710.1	FOLN	30..52	CDD:128570	5/26 (19%)
		KAZAL_FS	57..97	CDD:238052	17/40 (43%)
		EF-hand_7	148..218	CDD:290234	15/71 (21%)
		EFh	148..218	CDD:298682	15/71 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960