DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32354 and Fstl4

DIOPT Version :9

Sequence 1:	NP_729380.1	Gene:	CG32354 / 50302	FlyBaseID:	FBgn0052354	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_796033.2	Gene:	Fstl4 / 320027	MGIID:	2443199	Length:	841	Species:	Mus musculus

Alignment Length:	303	Identity:	70/303 - (23%)
Similarity:	99/303 - (32%)	Gaps:	98/303 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 RESCPVDCNSAPKDGPVCSSDGNVYNSTCEMKLKTCGQGVVKTSRKHCQSTRMCRESCWRVARPT 337
            ||..|....||.....:||     :.|.|.:. :|.||       ..||    |.|.|.....|.
Mouse    52 REGLPSPGLSASCGKKLCS-----HGSRCLLN-RTTGQ-------PSCQ----CLEVCRPRYMPV 99

  Fly   338 CGSDGRLYASPCKMRSSNC--GKHVFEVPLSYCMSQERHGASDAC-------------------- 380
            ||||||||.:.|::|.:.|  ||.:..|....|..:     .|.|
Mouse   100 CGSDGRLYGNHCELRRAACLLGKRIVSVHSKDCFLK-----GDMCTMAGYARLKNVLLALQSRRQ 159

  Fly   381 --PTECPKSDTDSSSQYVCGS-------DGNIYSSLCELKMLNCGPQRKSIQKVSMDKCKNRLTR 436
              |...|:....|..:.:..|       |||.:....||       .:..:::..||   ..|.|
Mouse   160 PLPQGTPRQSLASQKRLLVESLFKDLDADGNGHLGSLEL-------AQYVLKEQDMD---GSLNR 214

  Fly   437 C--KQLPPCKDFNS----LFGSIFSSKR--------NDKLCGTDAKTYNNECELAHATCLRGVNL 487
            |  ..|....|:||    ..|..:::.:        .||:..|...                |.|
Mouse   215 CSPSDLLRFDDYNSDGSLTLGEFYTAFQVIQLSLAPEDKVSVTTVT----------------VGL 263

  Fly   488 AHIGPCT---DLNSPT--KDCGDACTRADLEQQPVCGSDGNTF 525
            :.:..|.   ||..|.  |..|...:...||.....|.||:.:
Mouse   264 STVLTCAIRGDLRPPIIWKRNGLTLSFLGLEDINDFGEDGSLY 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:294071
		KAZAL	220..266	CDD:197624
		KAZAL_FS	326..>359	CDD:294071	16/34 (47%)
		KAZAL	380..430	CDD:197624	12/78 (15%)
		KAZAL	452..493	CDD:197624	5/48 (10%)
		KAZAL	502..>536	CDD:197624	6/24 (25%)
		KAZAL_FS	553..597	CDD:294071
		KAZAL	606..650	CDD:197624
Fstl4	NP_796033.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..54		1/1 (100%)
		KAZAL_FS	92..132	CDD:238052	16/39 (41%)
		EFh	178..242	CDD:298682	16/73 (22%)
		EF-hand_7	178..241	CDD:290234	16/72 (22%)
		IG_like	255..322	CDD:214653	14/68 (21%)
		Ig	266..322	CDD:143165	11/41 (27%)
		I-set	340..429	CDD:254352
		Ig2_Follistatin_like	357..432	CDD:143213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910