Protein Alignment CG32354 and Reck

DIOPT Version :10

• Sequence 1: NP_729380.1
• Gene: CG32354 / 50302
• FlyBaseID: FBgn0052354
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001402852.1
• Gene: Reck / 313488
• RGDID: 1308845
• Length: 972
• Species: Rattus norvegicus
• Alignment Length: 814
• Identity: 155/814 - (19%)
• Similarity: 235/814 - (28%)
• Gaps: 349/814 - (42%)

  Fly     1 MHHKQHLH----LHLQPPAPNATQTQAHGLGQTPSQIAR--CSHNHSPSLGLSFGGTKSQRQLF- 58
            :...|.:|    :| .||:......:.|...:..:.:.|  |:..:|    :|:|.|:|.::..
  Rat   265 LESSQSVHPGVTVH-PPPSTGLDGAKLHCCSKANTSVCRELCTKLYS----MSWGNTQSWQEFDR 324

  Fly    59 ------GALLAMFTLA-------------------------AFASTTS----GAVTDSPI---KI 85
                  |.:..:..||                         .|.|.|:    ||::|..:   ..
  Rat   325 ICEYNPGEVSMLACLADVREPCQLGCTNLTYCTNFNNRPTELFRSCTAQSDQGAMSDMRLWEKGS 389

  Fly    86 IRLP-AQAPVIRYRSADAAPNSLLINYRQDARPELSSTLMQAPGAAAAALE----------SLLR 139
            |::| ...||:..|:               .:|:|..       |.|.:|:          |::.
  Rat   390 IKMPFISIPVLDIRT---------------CQPDLWK-------AVACSLQIKPCHRKSRGSIIC 432

  Fly   140 EETEQQQLSQMGRRNRASNTGTG--------------NC------------------------PR 166
            :....:.|.:.|.:|:.....|.              ||                        |.
  Rat   433 KSDCVEILKKCGDQNKFPEAHTAESICEFLSPADDVENCIPLDTYLRPSALGNIIEEVTHPCNPN 497

  Fly   167 SCPPSITVGAEPVCGSDGLIYANICELRKKTCSRSGVSLIKDVRDGCERSKGSD----------- 220
            .||.:                 .:||:.:|.|......|......||:..:.||
  Rat   498 PCPAN-----------------ELCEVNRKGCPSGDPCLPYSCVQGCKLGEASDFIVRQGALIQV 545

  Fly   221 --------CKHRCSTEKDPVCGTDGRTYLNRCM----LRVQ-SCRVGLAAVKLSHVGPCSNTSAV 272
                    |...||      ||..|  .|..||    :.:| ||.||  ..:.||
  Rat   546 PSSAGEVGCYKICS------CGQSG--LLENCMEMHCIDLQKSCIVG--GKRKSH---------- 590

  Fly   273 RESCPVDCNSAPKDGPVCSSDGNVYNSTCEMKLKTCGQGVVKTSRKHCQSTRMCRE--------- 328
            ..|..:|||       |||....  |..|                    |||:|..
  Rat   591 GTSFTIDCN-------VCSCFAG--NLVC--------------------STRLCLSEHSSDDDRR 626

  Fly   329 -------SCWRVARPTCGSDGRLYASPCKMRSSNCGKHVFEVPLSYCMSQERHGASDAC-PTECP 385
                   :|.....|.|..:||.|.|.|..|......|.||  ...|:|:      |.| |..||
  Rat   627 AFTGLPCNCADQFVPVCAQNGRTYPSACIARCVGLQDHQFE--FGPCISK------DPCNPNLCP 683

  Fly   386 KSDTDSSSQYVCGSDGNIYSSLCELKMLNCGPQRKSIQKVSMDKCKNRLTRCKQLPPCKDFNSLF 450
            ||........||         |.......|          |..:|..|...|.|
  Rat   684 KSQRCVPKPQVC---------LTTFDKFGC----------SQYECVPRQLTCDQ----------- 718

  Fly   451 GSIFSSKRNDKLCGTDAKTYNNECELAHATCLRGVNLAHIGPCTDLNSPTKDCGDACTRADLEQQ 515
                   ..|.:|.||...::|.|.|..    ||.:|::.|||......|              :
  Rat   719 -------ARDPVCDTDHVEHSNLCTLYQ----RGKSLSYRGPCQPFCRTT--------------E 758

  Fly   516 PVCGSDGNTFASMC-EFKRRT-------CDLRVVPVSLKNCALTADCESDCDAQ---------PP 563
            ||||.:|.|::|:| .:..|.       |  :.|.|..::.|:|......|.:.         ||
  Rat   759 PVCGHNGETYSSVCAAYSDRVAVDYYGRC--QAVGVLSEHSAVTECAAVKCPSLSAIGCKPIIPP 821

  Fly   564 SFVC-------------------GSDNN---------LYKSECHMRKENCGKH----------VF 590
            ...|                   ....|         |.|...|:....|...          :.
  Rat   822 GACCPLCAGMLRVLFDKEKLDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYLSIESEIVIL 886

  Fly   591 VVPLKRCLAAFQLKGCARICPREFEPVCGSDNKT 624
            ::|:.....|.|::.|.:.. .:.|.:..||:.|
  Rat   887 IIPVDHYPKALQIEACNKEA-EKIESLINSDSPT 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:412159	9/60 (15%)
		KAZAL	220..266	CDD:197624	17/69 (25%)
		KAZAL_FS	326..>359	CDD:412159	10/48 (21%)
		KAZAL	380..430	CDD:197624	11/50 (22%)
		KAZAL	452..493	CDD:197624	11/40 (28%)
		KAZAL	502..>536	CDD:197624	9/41 (22%)
		KAZAL_FS	553..597	CDD:412159	10/90 (11%)
		KAZAL	606..650	CDD:197624	5/19 (26%)
Reck	NP_001402852.1	MFS	<617..699	CDD:475125	24/98 (24%)
		Amnionless	<802..>886	CDD:464340	9/83 (11%)