DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32354 and Fst

DIOPT Version :9

Sequence 1:	NP_729380.1	Gene:	CG32354 / 50302	FlyBaseID:	FBgn0052354	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_036693.1	Gene:	Fst / 24373	RGDID:	2633	Length:	344	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	85/345 - (24%)
Similarity:	134/345 - (38%)	Gaps:	87/345 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 DGRLYASPCKMRSSNCGKHVFEVPLSYCMSQERHGASDACPTECPKSDTDSSSQY----VCGSDG 401
            |....|..|.:|.:..|:  .:|.....:|:|...::....|...:.|.:.::.:    ..|...
  Rat    24 DRSAQAGNCWLRQAKNGR--CQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAP 86

  Fly   402 NIY--SSLCELKMLNCGPQRKSIQKVSMDKCKNRLTRCKQLPPCKDFNSLFGSIFSSKRNDKLCG 464
            |..  ...||  .::|||.:    |..|:| ||: .||...|.|.:..          ....:||
  Rat    87 NCIPCKETCE--NVDCGPGK----KCRMNK-KNK-PRCVCAPDCSNIT----------WKGPVCG 133

  Fly   465 TDAKTYNNECELAHATCLR--GVNLAHIG----PCTDLNSPTKD--------------CGDACTR 509
            .|.|||.|||.|..|.|..  .:.:.:.|    .|.|:..|...              |...|..
  Rat   134 LDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPE 198

  Fly   510 ADLEQQPVCGSDGNTFASMCEFKRRTCDL-RVVPVSLK-NCALTADCESDCDAQPPSFVCGSDNN 572
            ....:|.:||:||.|::|.|..::.||.| |.:.::.: .|.....||   |.|     ||..
  Rat   199 PSSSEQSLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCE---DIQ-----CGGG-- 253

  Fly   573 LYKSECHMRKENCGKHVFVVPLKRCLAAFQL-KG----CARICP--REFEPVCGSDNKTYLNDCF 630
                                  |:||..|:: :|    |..:||  :..||||.|||.||.::|.
  Rat   254 ----------------------KKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECA 296

  Fly   631 LEIENCRANQTVNVNYYGAC 650
            ::...|.:...:.|.:.|:|
  Rat   297 MKEAACSSGVLLEVKHSGSC 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:294071
		KAZAL	220..266	CDD:197624
		KAZAL_FS	326..>359	CDD:294071	5/17 (29%)
		KAZAL	380..430	CDD:197624	11/55 (20%)
		KAZAL	452..493	CDD:197624	13/46 (28%)
		KAZAL	502..>536	CDD:197624	10/47 (21%)
		KAZAL_FS	553..597	CDD:294071	7/43 (16%)
		KAZAL	606..650	CDD:197624	16/45 (36%)
Fst	NP_036693.1	FOLN	94..117	CDD:128570	11/30 (37%)
		KAZAL	117..164	CDD:197624	15/56 (27%)
		FOLN	167..190	CDD:128570	3/22 (14%)
		KAZAL	192..239	CDD:197624	14/46 (30%)
		KAZAL	270..316	CDD:197624	16/45 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..344		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810