DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32354 and Fstl3

DIOPT Version :9

Sequence 1:	NP_729380.1	Gene:	CG32354 / 50302	FlyBaseID:	FBgn0052354	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_446081.1	Gene:	Fstl3 / 114031	RGDID:	621811	Length:	256	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	70/304 - (23%)
Similarity:	107/304 - (35%)	Gaps:	109/304 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 VCGSDGNIYSSLCEL---KMLNCGPQRKSIQKVSMDKCKNRLTRCKQLPPCKDFNSLFGSIFSSK 457
            |.||..::...:|.|   |...|....|:  :||.::|            |..     |:|.::.
  Rat    24 VMGSGDSVPGGVCWLQQGKEATCSLVLKT--QVSREEC------------CAS-----GNINTAW 69

  Fly   458 RNDKLCGTDAKTYNNECELAHATCLRGVNLAHIGPCTDLNSPTKDCGDACTRADLEQQPVCGSDG 522
            .|....|       |:..|     |..:.|.|..||.| :....:||.......|..:|.|
  Rat    70 SNFTHPG-------NKISL-----LGFLGLVHCLPCKD-SCDGVECGPGKACRMLGGRPHC---- 117

  Fly   523 NTFASMCEFKRRTCDLRVVPVSLKNCALTADCESDCDAQPPSF-VCGSDNNLYKSECHMRKENCG 586
                                          :|.|:|:..|..| |||||...|:.||.:|...|.
  Rat   118 ------------------------------ECVSNCEGVPAGFQVCGSDGATYRDECELRTARCR 152

  Fly   587 KH--VFVVPLKRCLAAFQLKGCAR-ICPR---------------------------EFEPVCGSD 621
            .|  :.|:...||     .|.||: :|||                           ..:.:||::
  Rat   153 GHPDLRVMYRGRC-----QKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPPNPGQELCGNN 212

  Fly   622 NKTYLNDCFLEIENCRANQTVNVNYYGAC-GRPEAPS---TNFL 661
            |.||::.|.|....|...:::.|.:.|.| |.|:.|:   .||:
  Rat   213 NVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32354	NP_729380.1	KAZAL_FS	163..>200	CDD:294071
		KAZAL	220..266	CDD:197624
		KAZAL_FS	326..>359	CDD:294071
		KAZAL	380..430	CDD:197624	10/36 (28%)
		KAZAL	452..493	CDD:197624	8/40 (20%)
		KAZAL	502..>536	CDD:197624	5/33 (15%)
		KAZAL_FS	553..597	CDD:294071	17/46 (37%)
		KAZAL	606..650	CDD:197624	15/71 (21%)
Fstl3	NP_446081.1	KAZAL	118..165	CDD:197624	17/46 (37%)
Fstl3	NP_446081.1	KAZAL_FS	198..241	CDD:238052	10/42 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900