DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and dpr21

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001163838.2	Gene:	dpr21 / 8674044	FlyBaseID:	FBgn0260995	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	124/215 - (57%)
Similarity:	165/215 - (76%)	Gaps:	6/215 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDT 137
            ||||.|..:|||:|:|.:.:|:||::||.|||||||||||:|:|||...||||||||.:.:::.|
  Fly    51 PYFDTSATKNVTSLVGITGHLNCRIKNLGNKTVSWIRHRDLHLLTVSESTYTSDQRFTSIYNKQT 115

  Fly   138 EDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKF 202
            .||:||||:.|.||:|:||||:||.|...|.:..:||.|..:|||||::::|.|||:||||.:|.
  Fly   116 GDWSLQIKFPQLRDSGIYECQVSTTPPVGYTMVFSVVEPITSILGGPEIYIDLGSTVNLTCVIKH 180

  Fly   203 SPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASV 267
            .|:||..:.|.|:.:.|||||.||||||||||||:|||:||||.|.:||||:|:|.||||:..||
  Fly   181 LPDPPISVQWNHNNQEINYDSPRGGVSVITEKGDITTSYLLIQRASIADSGQYTCLPSNANSKSV 245

  Fly   268 RVHVLNVRAIISGEHPEAMQ 287
            .||:|      .|:||.|:|
  Fly   246 NVHIL------KGDHPAAVQ 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	52/94 (55%)
		IG_like	80..175	CDD:214653	53/94 (56%)
		IG_like	184..271	CDD:214653	53/86 (62%)
		IGc2	191..262	CDD:197706	46/70 (66%)
dpr21	NP_001163838.2	Ig	71..149	CDD:299845	47/77 (61%)
		IG_like	71..140	CDD:214653	44/68 (65%)
		IG_like	162..249	CDD:214653	53/86 (62%)
		IGc2	169..242	CDD:197706	48/72 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446146
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D77526at33392
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X190
	8	8.000