DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and KIRREL2

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_954649.3 Gene:KIRREL2 / 84063 HGNCID:18816 Length:708 Species:Homo sapiens


Alignment Length:389 Identity:85/389 - (21%)
Similarity:128/389 - (32%) Gaps:107/389 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 PYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDT 137
            |:| ...|.::..|:|:.|.|.|.:..... .|.|.:..    |.:|.             .:|.
Human    24 PHF-LQQPEDLVVLLGEEARLPCALGAYWG-LVQWTKSG----LALGG-------------QRDL 69

  Fly   138 EDWT--------------LQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVP--TATILGGPDL 186
            ..|:              |.|:..:..|...||||.:...:||...:|:|:||  ...:||||.:
Human    70 PGWSRYWISGNAANGQHDLHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSV 134

  Fly   187 HVDKGSTINLTCTVKFSPEPPAYIFWYH----------HEEVINYDSSRGGV-SVITEKGDVTTS 240
            .:..|...||||..:....|...:.|:.          |:.::. :.:.|.| |.:|     .|.
Human   135 SLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLK-EGTPGSVESTLT-----LTP 193

  Fly   241 FLLIQNADLADSGKYSCAPSNADVASVRVHVLNVRAIISGEHPEAMQTGSSG---CQ-------- 294
            |.....|......:....|:..|.| :.:.:.....:.....|..:|.|...   ||        
Human   194 FSHDDGATFVCRARSQALPTGRDTA-ITLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVT 257

  Fly   295 -YNW--------------LTIV----LLLGLVLCYSSQQCSSAVPASLTSSL--PLPSQLPLPAA 338
             |.|              |.:|    .|...|.|..|....||..::....|  |:....|.|  
Human   258 GYRWAKGGSPVLGARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEP-- 320

  Fly   339 AAATTTATGESASSE---------SVTAARASAATTTTTTATRKRCPAVKS-------CRQTAG 386
               .:...||.||..         .||..|...|....:.|| .|.|:|..       ||..||
Human   321 ---VSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGAT-LRLPSVGPEDAGDYVCRAEAG 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 22/108 (20%)
IG_like 80..175 CDD:214653 23/108 (21%)
IG_like 184..271 CDD:214653 19/97 (20%)
IGc2 191..262 CDD:197706 16/81 (20%)
KIRREL2NP_954649.3 IG_like 30..119 CDD:214653 22/106 (21%)
IGc2 38..106 CDD:197706 17/85 (20%)
I-set 126..224 CDD:254352 22/104 (21%)
Ig2_KIRREL3-like 141..223 CDD:143236 17/88 (19%)
Cell attachment site. /evidence=ECO:0000255 149..151 0/1 (0%)
Ig 231..306 CDD:299845 15/74 (20%)
IG_like 234..308 CDD:214653 15/73 (21%)
Ig 312..395 CDD:299845 20/75 (27%)
I-set 317..395 CDD:254352 19/70 (27%)
Ig 397..501 CDD:299845
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 545..601
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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