DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and dscama

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	298	Identity:	76/298 - (25%)
Similarity:	114/298 - (38%)	Gaps:	73/298 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HPLPLCVAWLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTHPK 69
            ||.|. ..||          ..|..::.......|:..||.....|         :.|.:|....
Zfish   252 HPAPK-YRWL----------KNNRPLESDSRFRQSVTGLLIERAQP---------SDTGSYVCEV 296

  Fly    70 W--------------MEPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGS 120
            |              .||.....:||.|...:|....|||.|.......:||.|:.|  .:..|
Zfish   297 WNSYGNAEVIGRLTVKEPLKAVVSPRKVKGSVGSQVSLSCSVTGSDEFELSWYRNGD--KINTG- 358

  Fly   121 YTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYEC-----QISTQPVRSYFVRLNVVVPTATI 180
                ::.|....:.::     |.:....|.|.|:|:|     ::|.|.    ||::.:...|..|
Zfish   359 ----ANIRMNGINKEN-----LVMDGMAKSDGGVYQCFSRKAKMSAQD----FVQVILEDGTPKI 410

  Fly   181 LG-------GPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVT 238
            |.       ||:      ..::|||.||.:|:|.  |.|...:||:..||....|..||.:|:|
Zfish   411 LSAFSEKVVGPN------DFVSLTCHVKGTPQPA--ITWTLDDEVVAKDSRHRIVHSITAEGNV- 466

  Fly   239 TSFLLIQNADLADSGKYSCAPSN-ADVASVRVHVLNVR 275
            .|:|.|.:..:.|||.|.|..:| |...|.:..: |||
Zfish   467 VSYLNISHIQVRDSGVYRCTCNNSAGTVSYQARI-NVR 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	24/99 (24%)
		IG_like	80..175	CDD:214653	24/99 (24%)
		IG_like	184..271	CDD:214653	30/87 (34%)
		IGc2	191..262	CDD:197706	27/71 (38%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352	13/78 (17%)
		IG_like	321..402	CDD:214653	24/96 (25%)
		I-set	408..502	CDD:333254	33/103 (32%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810