DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	291	Identity:	62/291 - (21%)
Similarity:	100/291 - (34%)	Gaps:	60/291 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IAHPL-----PLCVAWLLLLVVIVM----------SDMTNGGVQGPIEGYNSLDDLLTTTPTPG- 51
            ::|||     |..|.|....|.|..          .|....| :..:.|..||......:...|
Zfish    47 VSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAG-RASLHGKASLQIEQVRSEDQGW 110

  Fly    52 -QAALLLPTAPTAAYTHPKWME------PYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIR 109
             :..:|:.......:.:..|:.      |.|..:.|:.|.|..|.|..|:|.........|:|:|
Zfish   111 YECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLR 175

  Fly   110 HRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQI-STQPVRSYFVRLNV 173
            ..|               :..:|......|.:|.::...:.|.|.|.|:. |.|....:..||.|
Zfish   176 EGD---------------QLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLV 225

  Fly   174 VVPTATILGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDV- 237
            ..|...:....::.|:.......||..:..|....|. ||..|:.:.:            |.|:
Zfish   226 QGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYT-WYWEEDNVYF------------KNDLK 277

  Fly   238 ------TTSFLLIQNADLADSGKYSCAPSNA 262
                  ....|:|......|:|||:|:|||:
Zfish   278 LRVRIFIDGTLIIYRVKPEDAGKYTCSPSNS 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	22/95 (23%)
		IG_like	80..175	CDD:214653	23/95 (24%)
		IG_like	184..271	CDD:214653	20/86 (23%)
		IGc2	191..262	CDD:197706	18/77 (23%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	14/68 (21%)
		I-set	139..225	CDD:254352	24/100 (24%)
		I-set	229..321	CDD:333254	20/93 (22%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810