DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and dpr12

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_652462.3	Gene:	dpr12 / 50320	FlyBaseID:	FBgn0085414	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	110/290 - (37%)
Similarity:	157/290 - (54%)	Gaps:	42/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LPLCVAWLLLLV--------VIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTA 63
            |.||:..|||..        ::..:|.....::|.|.|.:.||:.|.::.:
  Fly    24 LLLCLPTLLLATTLEPDQKSILTDNDWKKLWMRGGINGDSKLDNNLDSSDS-------------- 74

  Fly    64 AYTHPKWMEPYFDPS--TPRNVTALMGKSAYLSCRVRNLAN-----KTVSWIRHRDIHILTVGSY 121
                     |.|:.|  ...|.|..:|.:|:|.|:|..:..     ..:||||.||.|||:.|:.
  Fly    75 ---------PMFEDSELMAHNTTVQLGGTAFLVCKVSGVDRVGVNWNQISWIRRRDWHILSSGAQ 130

  Fly   122 TYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQP-VRSYFVRLNVVVPTATILGGPD 185
            .||:|:||...|...:..||||||:.|:||.||||||:||.. :.|:||.|.||||.|.|||..:
  Fly   131 LYTNDERFAILHTPGSNMWTLQIKFVQRRDHGMYECQVSTPTGIISHFVNLQVVVPEAFILGSGE 195

  Fly   186 LHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLA 250
            ||||.||||||.|.::.||.||.|::|..::.:|||..||..:::.|..|..|.|.|:|:...:.
  Fly   196 LHVDMGSTINLVCIIEKSPTPPQYVYWQKNDRLINYVDSRRDITIETTPGPRTQSRLIIREPQVT 260

  Fly   251 DSGKYSCAPSNADVASVRVHVL---NVRAI 277
            |||.|:|:.||.:.||:.|.|.   |:.||
  Fly   261 DSGNYTCSASNTEPASIYVFVSKGDNMAAI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	44/100 (44%)
		IG_like	80..175	CDD:214653	45/100 (45%)
		IG_like	184..271	CDD:214653	38/86 (44%)
		IGc2	191..262	CDD:197706	30/70 (43%)
dpr12	NP_652462.3	IG	86..183	CDD:214652	44/96 (46%)
		Ig_3	193..271	CDD:404760	33/77 (43%)
		Ig strand B	204..208	CDD:409353	3/3 (100%)
		Ig strand C	219..223	CDD:409353	1/3 (33%)
		Ig strand E	250..254	CDD:409353	2/3 (67%)
		Ig strand F	264..269	CDD:409353	2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X190
	7	6.960