DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and wrapper

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	65/280 - (23%)
Similarity:	93/280 - (33%)	Gaps:	77/280 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PLPLCVAWLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTA------PTAA 64
            |.|: :.|.|           ||.|..|.....:...|:....:..||.|:...|      |..|
  Fly   160 PQPV-ITWRL-----------NGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVA 212

  Fly    65 --YTHPKWMEPYFDP--STPRNVT-ALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYT 124
              |.|     ..|.|  |.|:.|. ..:|..|:|.|.|......||.|..|.  ..:.:|:::.|
  Fly   213 NVYLH-----VLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHG--LPVALGAHSTT 270

  Fly   125 SDQRFQAT----HHQDTEDWTLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPD 185
            .:...|..    |:.:.....|.:|..:..|.|.|||:.|.|        ::|...:..:.|.|
  Fly   271 HESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQ--------ISVKSGSVELTGRP- 326

  Fly   186 LHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLA 250
                      :.|..|.:|               ...||...|.|..     |.|.|.|....|
  Fly   327 ----------MPCLFKINP---------------GTQSSTSHVLVWQ-----TESLLPIMEFKL- 360

  Fly   251 DSGKYSCAPSNADVASVRVH 270
               |:...|||.....||.:
  Fly   361 ---KFRQIPSNNVTRQVRTN 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	24/99 (24%)
		IG_like	80..175	CDD:214653	25/99 (25%)
		IG_like	184..271	CDD:214653	19/87 (22%)
		IGc2	191..262	CDD:197706	15/70 (21%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845
		IG_like	41..118	CDD:214653
		IG_like	145..218	CDD:214653	17/74 (23%)
		Ig	147..219	CDD:299845	17/75 (23%)
		I-set	224..323	CDD:254352	26/108 (24%)
		IGc2	236..314	CDD:197706	22/87 (25%)
		FN3	339..431	CDD:238020	15/48 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810