DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and LRIT3

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_940908.3 Gene:LRIT3 / 345193 HGNCID:24783 Length:679 Species:Homo sapiens


Alignment Length:339 Identity:72/339 - (21%)
Similarity:107/339 - (31%) Gaps:103/339 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 RVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWT--------------LQIKW 146
            |..:|.|..::.:.:..:..|...:|...|..|.........|.||              .:|..
Human   132 RTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIIL 196

  Fly   147 AQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPDL-------------------HVDK-- 190
            ..:.:....:|.||.      .:.|:.||..|.:|..|.:                   |..|  
Human   197 GLQDNPWFCDCHISK------MIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPS 255

  Fly   191 ------------GSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGD--VTTSF 241
                        ||.:.|.|.....|.|  .|.|      ...|||....:||.|..:  |..|.
Human   256 VMTSATKIMSALGSNVLLRCDATGFPTP--QITW------TRSDSSPVNYTVIQESPEEGVRWSI 312

  Fly   242 LLIQNADLADSGKYSCAPSNADVASVRVHVLNVRAII-----------SGEHPE-AMQTG----- 289
            :.:......|:|.|.|...|....|..|..:.|..|.           :|:||| .:|.|     
Human   313 MSLTGISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPDTSERTGDHPEWDVQPGSGRST 377

  Fly   290 --SSGCQYNWLTIVLLLGLVLCYSSQQCSSAVPASLTSSLPLPSQLPLPAAAAATTTATGESASS 352
              ||...|.|                 .||..|.|..|:    |.|..|:.|:.:.:....|..|
Human   378 SVSSASSYLW-----------------SSSFSPTSSFSA----STLSPPSTASFSLSPFSSSTVS 421

  Fly   353 ESVTAARASAATTT 366
            .:.|.:.:.:|:||
Human   422 STTTLSTSISASTT 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 15/91 (16%)
IG_like 80..175 CDD:214653 15/92 (16%)
IG_like 184..271 CDD:214653 26/121 (21%)
IGc2 191..262 CDD:197706 20/72 (28%)
LRIT3NP_940908.3 LRR 1 56..79
leucine-rich repeat 59..82 CDD:275378
LRR_8 61..117 CDD:290566
LRR 2 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3 104..128
LRR_8 105..165 CDD:290566 6/32 (19%)
LRR_4 105..146 CDD:289563 3/13 (23%)
leucine-rich repeat 107..130 CDD:275378
LRR 4 129..151 3/18 (17%)
LRR_4 131..170 CDD:289563 7/37 (19%)
leucine-rich repeat 131..154 CDD:275378 4/21 (19%)
LRR 5 152..175 4/22 (18%)
leucine-rich repeat 155..168 CDD:275378 3/12 (25%)
Ig 267..345 CDD:299845 23/85 (27%)
IG_like 267..345 CDD:214653 23/85 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 351..375 6/23 (26%)
FN3 486..550 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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