DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and DIP-zeta

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	79/264 - (29%)
Similarity:	112/264 - (42%)	Gaps:	43/264 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NG-GVQGPIEGYNSLDDLLTTTPTPGQAALLL----PTAPTA----AYTHPKWMEPYFDPSTPRN 82
            || |..||:.|..      |.:...|...:::    ...||:    ....|::.| |.:     |
  Fly    69 NGAGGGGPVAGSG------TGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTE-YIE-----N 121

  Fly    83 VTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATH--HQDTEDWTLQIK 145
            ||...|::..|.|.|:||.:..|:|:......||||.::..|.:.|...||  |.....|.|.|.
  Fly   122 VTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHIN 186

  Fly   146 WAQKRDAGMYECQISTQPVRSYFVRLNVVVP--TATILGGPDLHVDKGSTINLTCTVKFSPEPPA 208
            ...:.|.|.|.|||:|...::.|..||||||  ....|...|:.|.:|:.|:|.|....||.|
  Fly   187 NVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRP-- 249

  Fly   209 YIFWYHHEEVINYDSSRGGVS---VITE-KGDVTTSFLLIQNADLADSGKYSCAPSNA--DVASV 267
            .|.|...      |:||..::   ::.| :||.    |.|......|.|.|.|..||.  ...|.
  Fly   250 IIKWKRD------DNSRIAINKNHIVNEWEGDT----LEITRISRLDMGAYLCIASNGVPPTVSK 304

  Fly   268 RVHV 271
            |:.|
  Fly   305 RIKV 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	33/96 (34%)
		IG_like	80..175	CDD:214653	34/96 (35%)
		IG_like	184..271	CDD:214653	27/92 (29%)
		IGc2	191..262	CDD:197706	22/74 (30%)
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	34/100 (34%)
		Ig	130..200	CDD:143165	23/69 (33%)
		I-set	226..310	CDD:254352	28/95 (29%)
		IGc2	233..298	CDD:197706	23/76 (30%)
		Ig	313..410	CDD:299845
		IG_like	325..410	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810