DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	106/404 - (26%)
Similarity:	147/404 - (36%)	Gaps:	118/404 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 WLLLLVVIVMSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTHPKWMEPYFDP 77
            |||||..:..|       |......|:.|                          ||:..|.
  Fly     9 WLLLLQSVCFS-------QASFSELNNSD--------------------------PKFSGPI--- 37

  Fly    78 STPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTED--W 140
               .|.|..:|:.|.|:|.|.:|.:..|:|:|.....||::.::..|.:.|...:|   ||.  |
  Fly    38 ---NNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISH---TEHRIW 96

  Fly   141 TLQIKWAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGPDLHVD----------KGSTIN 195
            .|:|:..|:.|.|.|.|||:|.|::|....|:||||       ||: ||          .|..:.
  Fly    97 QLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVP-------PDI-VDYQTSQDVVRSTGQNVT 153

  Fly   196 LTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPS 260
            |||:....|.|.  |.|...|......|..|...|.:.:|...|.: .:|.:.:   |.|.|..|
  Fly   154 LTCSATGVPMPT--ITWRREEATPILISDDGDREVFSVEGQNLTLW-QVQRSHM---GAYLCIAS 212

  Fly   261 NA--DVASVRVH-VLNVRAIISGEHPEAMQTGSSGCQYNWL---TIVLLLGLVL---CYSSQQCS 316
            |.  ...|.||. |:|....|                  |.   ||.:.||..|   |.:..|
  Fly   213 NGVPPTVSKRVMLVVNFAPTI------------------WTRYDTIYVGLGQKLTLECITESQ-- 257

  Fly   317 SAVPASLTSSLPLPSQLPLPAAAAATTTATGESASSESVTAARASAATTTTTTATRKR-----CP 376
               |||:...| ..|||           ..|.|..|.||..........|....|::.     |.
  Fly   258 ---PASVNFWL-RDSQL-----------LQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICR 307

  Fly   377 AVKSCRQTAGRVLT 390
            |..:..|| .|::|
  Fly   308 AKNAMGQT-DRIIT 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	32/96 (33%)
		IG_like	80..175	CDD:214653	33/96 (34%)
		IG_like	184..271	CDD:214653	27/99 (27%)
		IGc2	191..262	CDD:197706	19/70 (27%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	31/88 (35%)
		Ig	39..122	CDD:299845	30/85 (35%)
		Ig	132..213	CDD:299845	23/94 (24%)
		IG_like	141..227	CDD:214653	23/91 (25%)
		IG_like	239..322	CDD:214653	27/100 (27%)
		IGc2	245..313	CDD:197706	20/84 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810