DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr6 and DIP-theta

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	63/196 - (32%)
Similarity:	93/196 - (47%)	Gaps:	15/196 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 RNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIK 145
            :|||..:.:.|.|.|.|.||....::|:|.....|||:.::..|.:.|...| |.:...|.|:|:
  Fly   137 QNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSIT-HAEKRAWILRIR 200

  Fly   146 WAQKRDAGMYECQISTQPVRSYFVRLNVVVPTATILGGP---DLHVDKGSTINLTCTVKFSPEPP 207
            ..::.|.|.|.|||:|.|::|....|:|||| ..||..|   |:.:.:||.:.|.|....||.|.
  Fly   201 DVKESDKGWYMCQINTDPMKSQVGYLDVVVP-PDILDYPTSTDMVIREGSNVTLKCAATGSPTPT 264

  Fly   208 AYIFWYHH-EEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASVRVHV 271
              |.|... .|:|...:   |...:...|    |||.|...:..:.|.|.|..||....:|...|
  Fly   265 --ITWRREGGELIPLPN---GAEAVAYNG----SFLTIAKVNRLNMGAYLCIASNGIPPTVSKRV 320

  Fly   272 L 272
            :
  Fly   321 M 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	31/92 (34%)
		IG_like	80..175	CDD:214653	32/93 (34%)
		IG_like	184..271	CDD:214653	25/90 (28%)
		IGc2	191..262	CDD:197706	21/71 (30%)
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	32/93 (34%)
		IG_like	137..230	CDD:214653	32/93 (34%)
		IG_like	240..324	CDD:214653	25/91 (27%)
		IGc2	247..310	CDD:197706	20/71 (28%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810