DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr6 and bdl

DIOPT Version :9

Sequence 1:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	67/327 - (20%)
Similarity:	114/327 - (34%)	Gaps:	78/327 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PIAHPLPLCVAWLLLLVVIV--------MSDMTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLP 58
            |...|:|..|.|......|.        .|::.||.:.           |:...|..|:|::.|.
  Fly    60 PFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLH-----------LVENHPEFGRASVNLT 113

  Fly    59 TAPTA--AYTHPKWMEPYFDPST--------------------PRNVTALMGKSAYLSCRVRNLA 101
            ....:  .:.|.:...|...||.                    |.|.|...|::|:..|.:::..
  Fly   114 AIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPE 178

  Fly   102 NKTVSWIRH----RDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQI--- 159
            |...||.:.    :::..|.         :||..     ..|.:|.|......|.|.|||::
  Fly   179 NSQASWYKDGVLLQEVQDLV---------RRFYM-----GPDGSLSIDPTMMSDLGEYECKVRNS 229

  Fly   160 --STQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYD 222
              ..|..:::   ||:......|...|::.:..|....|.|..:.:| |...:.|  .::.:.:|
  Fly   230 DGELQTAKAF---LNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANP-PLKNLRW--EKDGLLFD 288

  Fly   223 SSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSN---ADVASVRVHVLNVRAIISGEHPE 284
            |.  .|..:..|   ....|.....|...:|.|:|.|.|   .|..|..:.|:.:|..|....|:
  Fly   289 SY--NVPGVFYK---MNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPK 348

  Fly   285 AM 286
            |:
  Fly   349 AI 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	23/123 (19%)
		IG_like	80..175	CDD:214653	23/103 (22%)
		IG_like	184..271	CDD:214653	20/89 (22%)
		IGc2	191..262	CDD:197706	17/73 (23%)
bdl	NP_608822.1	IG_like	42..128	CDD:214653	15/78 (19%)
		Ig	43..131	CDD:299845	15/81 (19%)
		I-set	153..242	CDD:254352	22/105 (21%)
		Ig	157..242	CDD:299845	22/101 (22%)
		Ig_2	252..337	CDD:290606	21/92 (23%)
		IG_like	260..327	CDD:214653	17/74 (23%)
		I-set	341..428	CDD:254352	3/10 (30%)
		IGc2	356..419	CDD:197706
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810