DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and itgb4

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:XP_005166847.1 Gene:itgb4 / 335269 ZFINID:ZDB-GENE-030131-7209 Length:1931 Species:Danio rerio


Alignment Length:409 Identity:77/409 - (18%)
Similarity:126/409 - (30%) Gaps:152/409 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 MTNGGVQGPIEGYNSLDDLLTTTPTPGQAALLLPTAPTAAYTHPKWMEPYFDPSTPRNVTALMGK 89
            :|:|...|..:.:..::.:..|..:|| ..|..|....|..|.||.:...:.||...|       
Zfish  1210 VTDGRGDGKNQDFQKMEYVTQTATSPG-GRLYSPANIKAVATGPKNIRLNWKPSQNAN------- 1266

  Fly    90 SAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQ-RFQATHHQDTE--------DWTLQIK 145
                       ..|...||            |....|: :|........|        |:.:::.
Zfish  1267 -----------GYKVKYWI------------YGDPEDKAKFMDVKTPQAELTNLDPYCDYEMRVC 1308

  Fly   146 WAQKRDAGMY----ECQ----ISTQPVRSYFVRLNVVVPTAT------------ILGGPD----- 185
            .......|.|    :||    |..:|.|..|   ||:.||.|            |:.|.:     
Zfish  1309 GYNALGDGNYSDIIQCQTLEDIPGEPGRLAF---NVISPTVTQVSWAEPAEANGIITGYEVIYMP 1370

  Fly   186 LHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLA 250
            ::.||..|           .||..:       :|:....|               .|||:|...:
Zfish  1371 INEDKKPT-----------GPPKKV-------MIDNPKKR---------------MLLIENLQPS 1402

  Fly   251 DSGKYSCAPSN-----------ADVASVRVHVLNVRAIISGEHPE-AMQTGSSGCQYNWLTIVLL 303
            .:..|....||           .::||.....:::..|     |: .:....:|.:|:       
Zfish  1403 QTYCYKVRASNKVGWGPYREATINLASQPTRPMSIPII-----PDIPIVDAEAGEEYD------- 1455

  Fly   304 LGLVLCYSSQQCSSAVPASLTSSLPLPSQLPL----------------PAAAAATTTATGESASS 352
              ..|.||::     |..|.|||| .||...|                |.....:.:   .:.||
Zfish  1456 --SYLMYSNE-----VLRSPTSSL-RPSVTDLSDDQFVNGKWEQNFLFPGGGGGSLS---RNISS 1509

  Fly   353 ESVTAARASAATTTTTTAT 371
            .|.|.:.::..|..|..::
Zfish  1510 SSTTYSHSTPRTNVTNNSS 1528

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 18/111 (16%)
IG_like 80..175 CDD:214653 19/111 (17%)
IG_like 184..271 CDD:214653 16/102 (16%)
IGc2 191..262 CDD:197706 12/81 (15%)
itgb4XP_005166847.1 Integrin_beta 37..457 CDD:278776
EGF_2 <468..490 CDD:285248
EGF_2 545..573 CDD:285248
Integrin_B_tail 625..709 CDD:285239
Calx-beta 991..1064 CDD:295344
FN3 1242..1326 CDD:238020 19/113 (17%)
FN3 1331..1420 CDD:238020 24/124 (19%)
fn3 1640..1720 CDD:278470
fn3 1751..1835 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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