DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and Opcml

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:274 Identity:76/274 - (27%)
Similarity:115/274 - (41%) Gaps:56/274 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 LLPT-APTAA--YTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILT 117
            |:|| .|..:  .|.||.|:         |||...|:||.|.|.:.:...: |:|:....  ||.
Mouse    24 LVPTGVPVRSGDATFPKAMD---------NVTVRQGESATLRCTIDDRVTR-VAWLNRST--ILY 76

  Fly   118 VGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQIST--QPVRSYFVRLNVVVPTATI 180
            .|:..::.|.|.....:..|: :::.|:.....|.|.|.|.:.|  .|..|. |.|.|.||...:
Mouse    77 AGNDKWSIDPRVIILVNTPTQ-YSIMIQNVDVYDEGPYTCSVQTDNHPKTSR-VHLIVQVPPQIM 139

  Fly   181 LGGPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQ 245
            ....|:.|::||::.|.|.....|||.  :.|.|    ::....:|.||        ...:|.|.
Mouse   140 NISSDITVNEGSSVTLLCLAIGRPEPT--VTWRH----LSVKEGQGFVS--------EDEYLEIS 190

  Fly   246 NADLADSGKYSCAPSN----ADVASVRVHVLNVRAIISGEHPEAMQTGSSGCQYNWLTIVLLLGL 306
            :.....||:|.|:..|    .||..|::.| |....||    :|..||.|..|         .|:
Mouse   191 DIKRDQSGEYECSALNDVAAPDVRKVKITV-NYPPYIS----KAKNTGVSVGQ---------KGI 241

  Fly   307 VLCYSSQQCSSAVP 320
            :.|.     :||||
Mouse   242 LSCE-----ASAVP 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 26/96 (27%)
IG_like 80..175 CDD:214653 27/96 (28%)
IG_like 184..271 CDD:214653 24/90 (27%)
IGc2 191..262 CDD:197706 19/74 (26%)
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 26/92 (28%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 4/7 (57%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 8/34 (24%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/6 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 4/9 (44%)
FR4 125..132 CDD:409353 3/7 (43%)
Ig_3 135..206 CDD:404760 21/84 (25%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 1/6 (17%)
Ig strand C' 171..174 CDD:409353 1/6 (17%)
Ig strand F 198..206 CDD:409353 3/7 (43%)
Ig_3 223..300 CDD:404760 13/46 (28%)
putative Ig strand A 224..230 CDD:409353 2/9 (22%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353
Ig strand E 279..283 CDD:409353
Ig strand F 293..298 CDD:409353
Ig strand G 306..309 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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