DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr6 and Sdk1

DIOPT Version :9

Sequence 1:NP_001287018.1 Gene:dpr6 / 50296 FlyBaseID:FBgn0040823 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:324 Identity:75/324 - (23%)
Similarity:112/324 - (34%) Gaps:76/324 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 PRNVTALMGKSAYLSCRVRNLANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQI 144
            |.:.|...|.:|.|.|.|.......::|  .|..|||..||...   .||..     .|...|:|
Mouse   468 PVDTTVTDGMTAVLRCEVSGAPKPAITW--KRGNHILASGSVRI---PRFML-----LESGGLRI 522

  Fly   145 KWAQKRDAGMYEC-------QISTQPVRSYFVRLNVVVPTATILGGPDLHVDKGSTINLTCTVKF 202
            .....:|||.|.|       .::...:.:.:.|.::|.|.      .|..|.||:|..|.|....
Mouse   523 APVFIQDAGNYTCYAANTEASVNASAMLTV
WNRTSIVHPP------EDRVVIKGTTATLCCGATH 581

  Fly   203 SPEPPAYIFWYHHEEVINYDSSRGGVSVITEKGDVTTSFLLIQNADLADSGKYSC---APSNADV 264
            .|.......|.....||...||.   .::.||    ...|:|......|.|.|:|   :...:|.
Mouse   582 DPRTSLRYVWKKDNVVITASSSS---RIVVEK----DGSLVISQTWSGDIGDYTCEIISEGGSDS 639

  Fly   265 ASVRVHVL-------NVRAIISGEHPEAMQ-------TGSSGCQY----------NW-------- 297
            .:.|:.|:       |:.|.:|.....::.       .|:|...|          .|        
Mouse   640 RTARLEVIELPHPPQNLLASLSPARSHSVTLSWVRPFDGNSPVLYYIVQVSENNSPWKVHLSNVG 704

  Fly   298 --LTIVLLLGLVLCYSSQ-------QCSSAVPASLTSSLPLPSQLPLPAAAAATTTATGESASS 352
              :|.|.:.||....:.|       |......::.||.|.||.: | |:|......|:|.:..|
Mouse   705 PEMTGVTVSGLTPARTYQFRVCAVNQVGKGQYSTETSRLMLPEE-P-PSAPPKNIVASGRTNQS 766

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr6NP_001287018.1 V-set 79..174 CDD:284989 25/100 (25%)
IG_like 80..175 CDD:214653 25/101 (25%)
IG_like 184..271 CDD:214653 23/89 (26%)
IGc2 191..262 CDD:197706 18/73 (25%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653
Ig 197..247 CDD:299845
IG_like 281..357 CDD:214653
IGc2 294..347 CDD:197706
I-set 368..457 CDD:254352
Ig 388..454 CDD:143165
I-set 462..552 CDD:254352 24/93 (26%)
Ig 476..552 CDD:299845 22/85 (26%)
I-set 557..646 CDD:254352 25/101 (25%)
Ig 562..646 CDD:299845 23/96 (24%)
FN3 650..741 CDD:238020 13/90 (14%)
fn3 753..839 CDD:278470 3/14 (21%)
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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